2-Acetylthiazole
2-Acetylthiazole (CAS 24295-03-2, C5H5NOS) is a heterocyclic organic compound with a molecular weight of 127.16 g/mol. This chemical serves as a valuable building block in organic synthesis. It has been documented for use in the preparation of complex molecules, including triazolothiazoles and chiral alcohols, and is also employed in aldol condensation reactions. Available from Tech Serve Solutions with an assay of 99%, it is suitable for research and development purposes.

Synthesis of Triazolothiazoles
2-Acetylthiazole has been utilised as a precursor in the synthetic pathways leading to the formation of triazolothiazole derivatives. This highlights its utility in constructing fused heterocyclic systems.
Preparation of Chiral Alcohols
The compound finds application in reactions that yield chiral alcohols. Its participation in these synthetic routes is crucial for accessing stereochemically defined compounds.
Aldol Condensation Reactions
2-Acetylthiazole is employed as a reactant in aldol condensation reactions. This demonstrates its capability to participate in carbon-carbon bond-forming processes central to organic synthesis.
| Molecular weight | 127.16 |
|---|---|
| Empirical formula | C5H5NOS |
| Assay | 99% |
| Boiling point | 89-91 °C/12 mmHg(lit.) |
| Density | 1.227 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.548(lit.) |
| Application | 2-Acetylthiazole was used in the preparation of triazolothiazoles,1 chiral alcohols2 and in aldol condensation reactions3. |

Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetylthiazole used for?
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2-Acetylthiazole is used as a building block in organic synthesis, particularly for preparing triazolothiazoles, chiral alcohols, and in aldol condensation reactions.
What are the CAS number and formula for 2-Acetylthiazole?
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The CAS number for 2-Acetylthiazole is 24295-03-2, and its empirical formula (Hill notation) is C5H5NOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Acetylthiazole with an assay of 99%. This product is typically considered a research or technical grade chemical and is not supplied as USP, BP, or EP grade.
What are the safety considerations when handling 2-Acetylthiazole?
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2-Acetylthiazole is classified as a Warning substance, with hazards including H302 (Harmful if swallowed), H317 (May cause an allergic skin reaction), and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
How is 2-Acetylthiazole packed, shipped, and exported?
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Tech Serve Solutions ensures secure and compliant packaging for shipping and export, adhering to all relevant regulations for chemical substances. Specific packing details can be provided upon request.
How can I request a sample or quote for 2-Acetylthiazole?
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To request a sample or a quote for 2-Acetylthiazole, please contact our sales team through the TSS website or by calling our customer service line.
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