2-Acetylthiophene
2-Acetylthiophene (CAS: 88-15-3), with the molecular formula C6H6OS and a molecular weight of 126.18 g/mol, is a valuable organosulfur compound. This thiophene derivative serves as a key intermediate in various chemical synthesis pathways. Its primary applications lie in the development of pharmaceuticals and agrochemicals, owing to its utility as a versatile heterocyclic building block in complex molecule construction. Available from Tech Serve Solutions with a standard assay of 98%.
- IUPAC
- Methyl-2-thienyl ketone
- Synonyms
- Methyl-2-thienyl ketone

Pharmaceutical Intermediates
2-Acetylthiophene is widely utilised as a foundational building block in the synthesis of active pharmaceutical ingredients (APIs). Its heterocyclic structure allows for diverse functionalisation, enabling the creation of complex drug molecules.
Agrochemical Synthesis
This compound finds application in the development of novel pesticides and herbicides. The thiophene moiety can be incorporated into various agrochemical structures to enhance efficacy and target specificity.
Organic Synthesis Research
As a versatile heterocyclic building block, 2-Acetylthiophene is employed in academic and industrial research for exploring new synthetic routes and developing novel organic compounds with potential applications.
| Molecular weight | 126.18 |
|---|---|
| Empirical formula | C6H6OS |
| Assay | 98% |
| Boiling point | 214 °C(lit.) |
| Density | 1.168 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.565(lit.) |
| Melting point | 10-11 °C(lit.) |

Hazard statements
- H300Fatal if swallowed
- H311Toxic in contact with skin
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 96 °C / 204.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetylthiophene primarily used for?
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2-Acetylthiophene is primarily used as an intermediate in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It functions as a versatile heterocyclic building block.
What is the CAS number and molecular formula for 2-Acetylthiophene?
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The CAS number for 2-Acetylthiophene is 88-15-3, and its molecular formula is C6H6OS.
What grade and purity does Tech Serve Solutions supply for 2-Acetylthiophene?
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Tech Serve Solutions supplies 2-Acetylthiophene with a standard assay of 98%. This product is not represented as USP, BP, or EP grade.
How should 2-Acetylthiophene be handled safely?
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2-Acetylthiophene is classified as Danger with hazards including H300 (Fatal if swallowed), H311 (Toxic in contact with skin), and H331 (Toxic if inhaled). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be used. Handle in a well-ventilated area or under a fume hood.
Is 2-Acetylthiophene classified as a controlled substance?
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Based on the provided data, 2-Acetylthiophene (CAS: 88-15-3) is not explicitly listed as a controlled or scheduled substance. However, users should always verify local regulations.
How is 2-Acetylthiophene packed, shipped, and exported?
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2-Acetylthiophene is packed and shipped according to its hazard classification (UN 2810, 6.1, PG II). Tech Serve Solutions exports chemicals globally, adhering to all international shipping regulations.
How can I request a quote or sample of 2-Acetylthiophene?
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To request a quote or a sample of 2-Acetylthiophene, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels, providing your specific requirements.
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