2-Acetylphenothiazine
2-Acetylphenothiazine (CAS: 6631-94-3) is a heterocyclic organic compound with the molecular formula C14H11NOS and a molecular weight of 241.31 g/mol. This compound is primarily utilised as a building block in chemical synthesis and has been investigated for its role as a NADPH oxidase (NOX) inhibitor in scientific research. It is also employed in the creation of novel phenothiazine derivatives.
NADPH Oxidase (NOX) Inhibition
2-Acetylphenothiazine has been documented for its use as an inhibitor of NADPH oxidase (NOX) in studies examining human platelet functional responses and intracellular signalling pathways. This application is crucial for understanding cellular signalling mechanisms.
Synthesis of Heterocyclic Derivatives
This compound serves as a valuable precursor in the synthesis of complex organic molecules. Specifically, it has been utilised in the preparation of 2-phenothiazin-2′-yl-cinchoninic acid derivatives, highlighting its utility in medicinal chemistry research.
Chemical Synthesis Building Block
As a versatile heterocyclic building block, 2-Acetylphenothiazine is employed in various organic synthesis routes for the development of novel chemical entities. Its structure lends itself to further functionalisation.
| Molecular weight | 241.31 |
|---|---|
| Empirical formula | C14H11NOS |
| Assay | 95% |
| Application | 2-Acetylphenothiazine was used as a NADPH oxidase (NOX) inhibitor in human platelet functional responses and intracellular signaling pathways1. It was also used in the synthesis of 2-phenothiazin-2′-yl-cinchoninic acid derivatives2. |
| Melting point | 180-185 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-52/53 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Acetylphenothiazine used for?
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2-Acetylphenothiazine is used as a NADPH oxidase (NOX) inhibitor in research and as a building block in chemical synthesis, particularly for creating phenothiazine derivatives.
What is the CAS number and molecular formula for 2-Acetylphenothiazine?
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The CAS number for 2-Acetylphenothiazine is 6631-94-3, and its molecular formula is C14H11NOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Acetylphenothiazine with an assay of 95%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling requirements for 2-Acetylphenothiazine?
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2-Acetylphenothiazine is classified as a Warning substance (GHS07) and is harmful if swallowed (H302) and harmful to aquatic life with long-lasting effects (H412). Appropriate personal protective equipment should be used, and handling should avoid release into the environment (P273).
Is 2-Acetylphenothiazine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Acetylphenothiazine, serving customers worldwide.
How can I request a sample or quote for 2-Acetylphenothiazine?
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To request a sample or a quotation for 2-Acetylphenothiazine, please contact our sales department via the website or direct email, providing your specific requirements.
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