2,6-Difluoro-3-ethoxyphenylboronic acid

CAS 849062-00-6C8H9BF2O3Chemical Synthesis

2,6-Difluoro-3-ethoxyphenylboronic acid (CAS 849062-00-6) is an organoboron compound with the molecular formula C8H9BF2O3 and a molecular weight of 201.96. This aryl boronic acid derivative serves as a valuable building block in organic synthesis. It is particularly useful in cross-coupling reactions, such as Suzuki-Miyaura couplings, for the formation of carbon-carbon bonds. Its specific substitution pattern makes it a targeted intermediate in the synthesis of complex organic molecules.

Synonyms: C8H9BF2O32,6-Difluoro-3-ethoxyphenylboronic acid

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2,6-Difluoro-3-ethoxyphenylboronic acid (C8H9BF2O3) — chemical structure, CAS 849062-00-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Aryl Boronic AcidsBoronic AcidsChemical SynthesisOrganometallic Reagents

01 /Applications

Suzuki-Miyaura Coupling Reagent

Utilised as a key coupling partner in Suzuki-Miyaura reactions to introduce the 2,6-difluoro-3-ethoxyphenyl moiety into various organic frameworks. This enables the construction of novel biaryl systems and complex molecular architectures.

Intermediate in Pharmaceutical Synthesis

Serves as a crucial intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates. The difluoroethoxy substitution can influence pharmacokinetic properties and target interactions.

Building Block for Agrochemicals

Employed in the development and manufacturing of advanced agrochemicals. Its unique structural features can contribute to the efficacy and selectivity of herbicides, insecticides, and fungicides.

Material Science Applications

Can be incorporated into the synthesis of functional organic materials. The electronic properties conferred by the fluorine and ethoxy substituents may be exploited in areas like organic electronics.

02 /Properties

Molecular weight	201.96
Empirical formula	C8H9BF2O3

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

849062-00-6

MDL number

MFCD07369735

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,6-Difluoro-3-ethoxyphenylboronic acid used for?

This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and potentially advanced materials.

What are the CAS number and formula for 2,6-Difluoro-3-ethoxyphenylboronic acid?

The CAS number is 849062-00-6, and the empirical formula (Hill notation) is C8H9BF2O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are available upon request and are not represented as USP, BP, or EP grade.

What are the safety and handling precautions for this chemical?

2,6-Difluoro-3-ethoxyphenylboronic acid is classified as Danger (GHS05) with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area.

How is this chemical packed, shipped, and exported?

As per UN 3261, 8 / PGII classification, this chemical is packed and shipped according to relevant dangerous goods regulations for corrosive solids, acidic, organic, n.o.s. Tech Serve Solutions is experienced in global export.

How can I request a sample or quote for 2,6-Difluoro-3-ethoxyphenylboronic acid?

To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (849062-00-6).