2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid
2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid (CAS: 870778-99-7) is a fluorinated aryl boronic acid derivative with a molecular weight of 298.48 g/mol. It serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions like Suzuki-Miyaura couplings. Its unique structure, featuring both fluorine atoms and a substituted benzyloxy group, makes it useful for introducing complex functionalities in the development of novel chemical entities for research and pharmaceutical applications.
- Synonyms
- 2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid

Organic Synthesis Intermediate
This compound is primarily used as an intermediate in complex organic syntheses. It participates effectively in palladium-catalysed cross-coupling reactions, enabling the formation of carbon-carbon bonds.
Pharmaceutical Research
It serves as a key building block in the discovery and development of new pharmaceutical agents. Its specific structural features allow for the precise modification of potential drug candidates.
Material Science
The compound can be employed in the synthesis of advanced materials where specific electronic or structural properties are desired, leveraging the influence of the fluoro and boronic acid functionalities.
| Molecular weight | 298.48 |
|---|---|
| Empirical formula | C13H10BClF2O3 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid used for?
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2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid is used as a valuable building block in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura coupling, and in the research and development of novel chemical entities for pharmaceuticals and materials science.
What are the CAS number and formula for this chemical?
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The CAS number for 2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid is 870778-99-7 and its empirical formula is C13H10BClF2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and technical applications. The specific assay and purity are available on the product's Certificate of Analysis, and it is not supplied as USP, BP, or EP grade.
How should 2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid be handled?
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Handle 2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK 2 in Germany, indicating a hazard to water.
How is this chemical packed and shipped?
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Tech Serve Solutions packs and ships this chemical according to international regulations for hazardous materials, ensuring safe transit for domestic and export orders.
How can I request a sample or quote for this product?
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To request a sample or a quotation for 2,6-Difluoro-3-(2′-chlorobenzyloxy)phenylboronic acid, please contact our sales department through the website or by calling our main line.
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