2,6-Difluoro-3-(2′-fluorobenzyloxy)phenylboronic acid
2,6-Difluoro-3-(2′-fluorobenzyloxy)phenylboronic acid (CAS: 836615-83-9) is a substituted aryl boronic acid with the molecular formula C13H10BF3O3 and a molecular weight of 282.02. This organoboron compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its specific trifluorinated benzyl ether substitution pattern makes it a useful intermediate for introducing complex fluorinated motifs into target molecules, finding utility in materials science and medicinal chemistry research.
- Synonyms
- C13H10BF3O32,6-Difluoro-3-(2-fluorobenzyloxy)phenylboronic acid

Suzuki-Miyaura Cross-Coupling Reagent
Utilised as a coupling partner in Suzuki-Miyaura reactions to form new carbon-carbon bonds. This enables the synthesis of complex biaryl structures and other valuable organic frameworks.
Intermediate in Pharmaceutical Synthesis
Serves as a key intermediate in the development of novel pharmaceutical agents. The presence of fluorine atoms can influence pharmacokinetic properties such as metabolic stability and lipophilicity.
Building Block for Materials Science
Incorporated into the synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) or other functional organic materials where specific electronic or optical properties are desired.
Research and Development
Employed in academic and industrial research laboratories for the exploration of new synthetic methodologies and the discovery of novel chemical entities.
| Molecular weight | 282.02 |
|---|---|
| Empirical formula | C13H10BF3O3 |
| Melting point | 120-124 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Difluoro-3-(2′-fluorobenzyloxy)phenylboronic acid primarily used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, and as an intermediate in the development of pharmaceuticals and advanced materials.
What is the CAS number and molecular formula for 2,6-Difluoro-3-(2′-fluorobenzyloxy)phenylboronic acid?
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The CAS number is 836615-83-9 and the molecular formula is C13H10BF3O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 2,6-Difluoro-3-(2′-fluorobenzyloxy)phenylboronic acid be handled?
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This compound is a warning irritant. Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Avoid breathing dust or vapours. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,6-Difluoro-3-(2′-fluorobenzyloxy)phenylboronic acid.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or call us directly. Provide the product name and CAS number (836615-83-9) for prompt service.
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