2,5-Dichlorothiophene-3-sulfonyl chloride
2,5-Dichlorothiophene-3-sulfonyl chloride (CAS: 56946-83-9) is a halogenated heterocyclic compound with the molecular formula C4HCl3O2S2 and a molecular weight of 251.54 g/mol. This organosulfur compound serves as a valuable building block in organic synthesis, particularly for the creation of complex molecules. It is primarily utilised in research and development settings for the construction of novel chemical entities, especially within the pharmaceutical and agrochemical sectors.
- Synonyms
- C4HCl3O2S2

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of various organic compounds. Its sulfonyl chloride group readily reacts with nucleophiles, enabling the introduction of the dichlorothiophene moiety into target molecules.
Pharmaceutical Research
Employed in the development of new pharmaceutical candidates. The thiophene scaffold is present in numerous biologically active compounds, making this reagent useful for medicinal chemistry research.
Agrochemical Development
Serves as a building block in the design and synthesis of novel agrochemicals. Research into new herbicides, pesticides, and fungicides may incorporate this chemical structure.
Materials Science
Potentially used in the synthesis of functional organic materials, such as polymers or dyes, where the electronic properties of the thiophene ring can be exploited.
| Molecular weight | 251.54 |
|---|---|
| Empirical formula | C4HCl3O2S2 |
| Assay | 97% |
| Boiling point | 256-257 °C(lit.) |
| Density | 1.697 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.595(lit.) |
| Storage temperature | 2-8°C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 1760 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dichlorothiophene-3-sulfonyl chloride used for?
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2,5-Dichlorothiophene-3-sulfonyl chloride (CAS: 56946-83-9) is primarily used as a versatile building block in organic synthesis for the preparation of various organic compounds, particularly in pharmaceutical and agrochemical research.
What is the CAS number and chemical formula for 2,5-Dichlorothiophene-3-sulfonyl chloride?
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The CAS number is 56946-83-9 and the empirical formula is C4HCl3O2S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Dichlorothiophene-3-sulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and general laboratory use.
How should 2,5-Dichlorothiophene-3-sulfonyl chloride be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires full personal protective equipment, including face shields, chemical-resistant gloves, and appropriate respiratory protection. Always consult the Safety Data Sheet before use.
Is 2,5-Dichlorothiophene-3-sulfonyl chloride available for export?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 2,5-Dichlorothiophene-3-sulfonyl chloride.
How can I request a quote or sample?
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To request a quote or a sample of 2,5-Dichlorothiophene-3-sulfonyl chloride, please contact our sales department through the website or by phone.
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