1-Benzylpyrazole-4-boronic acid pinacol ester

CAS 761446-45-1C16H21BN2O2Chemical Synthesis

1-Benzylpyrazole-4-boronic acid pinacol ester (CAS 761446-45-1, C16H21BN2O2) is a heteroaryl boronate ester with a molecular weight of 284.16 g/mol. Supplied at 95% purity, this organometallic reagent is primarily utilised in chemical synthesis, particularly in cross-coupling reactions. Its structural features make it a valuable building block for creating complex organic molecules in research and development settings.

IUPAC: 1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole,1-Benzyl-4-pyrazole boronic acid pinacol ester
Synonyms: 1-Benzyl-4-pyrazole boronic acid pinacol ester1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

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1-Benzylpyrazole-4-boronic acid pinacol ester (C16H21BN2O2) — chemical structure, CAS 761446-45-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents

01 /Applications

Suzuki-Miyaura Coupling Reagent

1-Benzylpyrazole-4-boronic acid pinacol ester serves as a key coupling partner in Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of carbon-carbon bonds by reacting with aryl or vinyl halides.

Intermediate in Organic Synthesis

This compound acts as a versatile intermediate for the synthesis of diverse organic structures, including pharmaceuticals and agrochemicals. Its pyrazole core and boronate ester functionality enable further chemical transformations.

Heterocycle Synthesis

It is employed in the construction of complex heterocyclic compounds. The pyrazole moiety can be incorporated into larger molecular frameworks, offering pathways to novel chemical entities.

02 /Properties

Molecular weight	284.16
Empirical formula	C16H21BN2O2
Assay	95%
Melting point	86-90 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

761446-45-1

MDL number

MFCD03789252

PubChem substance

24882750

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-Benzylpyrazole-4-boronic acid pinacol ester used for?

This compound is primarily used as a coupling reagent in Suzuki-Miyaura reactions and as an intermediate in organic synthesis, particularly for constructing heterocyclic compounds.

What is the CAS number and formula for 1-Benzylpyrazole-4-boronic acid pinacol ester?

The CAS number is 761446-45-1 and the molecular formula is C16H21BN2O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1-Benzylpyrazole-4-boronic acid pinacol ester at a purity of 95%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP.

What are the safety considerations when handling this product?

Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use an N95 (US) or P1 (EN143) respirator filter if airborne exposure is possible. Avoid contact with skin and eyes.