2,5-Dichlorothiophene
2,5-Dichlorothiophene (CAS: 3172-52-9) is a halogenated heterocyclic compound with the molecular formula C4H2Cl2S and a molecular weight of 153.03 g/mol. This thiophene derivative serves as a versatile building block in organic synthesis. It is primarily utilised in chemical synthesis, particularly for the construction of more complex molecules within pharmaceutical and materials science research. Its defined structure and reactivity make it a valuable intermediate for creating novel compounds.
- Synonyms
- C4H2Cl2S2,5-dichlorothiophene

Organic Synthesis Intermediate
2,5-Dichlorothiophene is employed as a key intermediate in the synthesis of various organic compounds. Its dichlorinated thiophene structure allows for diverse functionalisation reactions, enabling the creation of complex molecular architectures.
Pharmaceutical Research
This compound finds application in the development of novel pharmaceutical agents. It can be incorporated into molecular structures being investigated for therapeutic properties, leveraging the thiophene core's presence in many bioactive molecules.
Materials Science
As a heterocyclic building block, 2,5-Dichlorothiophene is utilised in the research and development of new materials. Its structure can contribute to the electronic or physical properties of polymers and other advanced materials.
| Molecular weight | 153.03 |
|---|---|
| Empirical formula | C4H2Cl2S |
| Assay | 98% |
| Boiling point | 162 °C(lit.) |
| Density | 1.442 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.562(lit.) |
| Storage temperature | 2-8°C |

Hazard statements
- H226Flammable liquid and vapour
| Flash point | 59 °C / 138.2 °F |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dichlorothiophene primarily used for?
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2,5-Dichlorothiophene (CAS: 3172-52-9) is primarily used as a building block in organic synthesis for the creation of complex molecules, particularly in pharmaceutical research and materials science.
What is the CAS number and molecular formula for 2,5-Dichlorothiophene?
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The CAS number for 2,5-Dichlorothiophene is 3172-52-9, and its molecular formula is C4H2Cl2S.
What grade and purity does Tech Serve Solutions supply for 2,5-Dichlorothiophene?
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Tech Serve Solutions supplies 2,5-Dichlorothiophene with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2,5-Dichlorothiophene be handled and stored?
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2,5-Dichlorothiophene is a flammable liquid and vapour (H226). It should be handled with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Store at 2-8°C.
How is 2,5-Dichlorothiophene packed, shipped, and exported?
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2,5-Dichlorothiophene is packed and shipped according to relevant regulations for flammable liquids. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a quote or sample for 2,5-Dichlorothiophene?
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Please contact our sales team or use the online request form on our website to inquire about pricing, bulk quantities, or to request a sample of 2,5-Dichlorothiophene.
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