2,5-Dibromotoluene
2,5-Dibromotoluene (CAS 615-59-8), with the molecular formula CH₃C₆H₃Br₂, is a halogenated aromatic hydrocarbon. This compound serves as a valuable intermediate in organic synthesis. Its primary applications include use as an internal standard in analytical chemistry, particularly for quantifying cyanide and thiocyanate via GC-MS, and as a building block in the preparation of specialised monomers for advanced materials like liquid-crystal polymers.
- Synonyms
- CH3C6H3Br2
Analytical Standard
2,5-Dibromotoluene is employed as an internal standard for the accurate quantification of cyanide and thiocyanate in human saliva samples using Gas Chromatography-Mass Spectrometry (GC-MS).
Monomer Synthesis
It is used in the synthesis of 2,5-bis(4′-alkoxycarbonylphenyl)styrenes. These styrenes are essential monomers required for the preparation of mesogen-jacketed liquid-crystal polymers, a class of advanced materials.
Organic Building Block
As a dibrominated toluene derivative, it functions as a versatile building block in organic synthesis, enabling the introduction of specific functional groups and structural motifs.
| Molecular weight | 249.93 |
|---|---|
| Linear formula | CH3C6H3Br2 |
| Assay | 98% |
| Boiling point | 135-136 °C/35 mmHg(lit.) |
| Density | 1.815 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.602(lit.) |
| Application | 2,5-Dibromotoluene has been used:• as internal standard for quantification of cyanide and thiocyanate in human saliva by GC-MS1• in the preparation of 2,5-bis(4′-alkoxycarbonylphenyl)styrenes, monomers required for the synthesis of mesogen-jacketed liquid-crystal polymers2 |
| Melting point | 5-6 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dibromotoluene used for?
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2,5-Dibromotoluene is used as an internal standard for quantifying cyanide and thiocyanate in saliva by GC-MS, and in the preparation of monomers for liquid-crystal polymers.
What are the CAS number and chemical formula for 2,5-Dibromotoluene?
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The CAS number is 615-59-8, and the linear chemical formula is CH₃C₆H₃Br₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Dibromotoluene with an assay of 98%. This is typically a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2,5-Dibromotoluene be handled safely?
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2,5-Dibromotoluene is a Warning substance (GHS07) with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Always wear appropriate personal protective equipment, including eyeshields and gloves, and use in a well-ventilated area or with suitable respiratory protection.
Is 2,5-Dibromotoluene a controlled substance?
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The provided data does not indicate that 2,5-Dibromotoluene is a controlled substance.
How can I request a quote or sample for 2,5-Dibromotoluene?
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To request a quote or sample of 2,5-Dibromotoluene, please contact the Tech Serve Solutions sales team through our website or by phone.
How is 2,5-Dibromotoluene shipped?
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2,5-Dibromotoluene is exported globally by Tech Serve Solutions. Specific shipping and packaging details are available upon request, subject to regulatory compliance.
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