2,5-Dichloro-3-methylthiophene
2,5-Dichloro-3-methylthiophene (CAS: 17249-90-0), with the molecular formula C5H4Cl2S and a molecular weight of 167.06 g/mol, is a halogenated heterocyclic building block. This compound is primarily utilised in chemical synthesis and research laboratories for the development of novel organic molecules and complex chemical structures. Its specific properties make it a valuable intermediate in various synthetic pathways.
- Synonyms
- C5H4Cl2S2,5-Dichloro-3-methyl-ThiopheneThiophene, 2,5-dichloro-3-methyl-

Organic Synthesis Intermediate
Serves as a key building block in the synthesis of more complex organic molecules. Its dichlorinated thiophene structure allows for diverse functionalisation in multistep synthetic routes.
Research and Development
Employed in academic and industrial research settings for exploring new chemical reactions and developing novel compounds, particularly within the fields of medicinal chemistry and materials science.
Heterocyclic Chemistry
Utilised as a versatile reagent in the study and application of thiophene derivatives. The presence of chlorine atoms offers opportunities for various coupling reactions and substitutions.
| Molecular weight | 167.06 |
|---|---|
| Empirical formula | C5H4Cl2S |
| Assay | 96% |
| Density | 1.331 g/mL at 25 °C |
| Refractive index | n20/D 1.555 |
| Storage temperature | 2-8°C |


Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 76 °C / 168.8 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dichloro-3-methylthiophene used for?
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2,5-Dichloro-3-methylthiophene is used as an intermediate in organic synthesis and in research and development for creating novel compounds, particularly within heterocyclic chemistry.
What is the CAS number and molecular formula for 2,5-Dichloro-3-methylthiophene?
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The CAS number is 17249-90-0, and the molecular formula is C5H4Cl2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Dichloro-3-methylthiophene with a minimum assay of 96%. This product is intended for research and technical applications and is not represented as USP, BP, or EP grade.
How should 2,5-Dichloro-3-methylthiophene be handled safely?
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Handling requires extreme caution due to its hazardous nature. It is corrosive and toxic if swallowed, causing serious eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, is essential. Work in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive guidelines.
How is 2,5-Dichloro-3-methylthiophene packed and shipped?
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Products are carefully packed according to international shipping regulations for hazardous materials. 2,5-Dichloro-3-methylthiophene is shipped under UN 2810, hazard class 6.1, packing group III.
How can I request a sample or quote for 2,5-Dichloro-3-methylthiophene?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels. Please provide your contact details and the quantity required.
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