2,5-Dibromothiophene
2,5-Dibromothiophene (CAS: 3141-27-3) is a halogenated heterocyclic organic compound with the molecular formula C4H2Br2S and a molecular weight of 241.93 g/mol. This thiophene derivative serves as a valuable building block in organic synthesis, particularly for constructing more complex molecules. Its reactivity makes it useful in the development of various chemical compounds and materials.
- Synonyms
- C4H2Br2S2,5-Dibromo-tiofen2,5-Dibromothiophen

Organic Synthesis Intermediate
2,5-Dibromothiophene is extensively employed as a versatile intermediate in the synthesis of diverse organic compounds. Its bromine atoms can be readily substituted or involved in coupling reactions, facilitating the construction of complex molecular architectures.
Material Science Research
This compound is utilized in the preparation of novel organic materials, including conductive polymers and organic semiconductors. The thiophene core is a common motif in materials science, and dibromination allows for controlled polymerisation or functionalisation.
Pharmaceutical Precursor
As a heterocyclic building block, 2,5-Dibromothiophene can act as a precursor in the multi-step synthesis of potential pharmaceutical agents. Its structure can be incorporated into drug candidates for various therapeutic areas.
| Molecular weight | 241.93 |
|---|---|
| Empirical formula | C4H2Br2S |
| Assay | 94% |
| Grade | Vetec™ reagent grade |
| Boiling point | 211 °C(lit.) |
| Density | 2.147 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.629(lit.) |
| Melting point | −6 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Flash point | 99 °C / 210.2 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dibromothiophene used for?
+
2,5-Dibromothiophene is primarily used as a building block in organic synthesis, a precursor for materials science research, and potentially in the synthesis of pharmaceutical intermediates.
What is the CAS number and formula for 2,5-Dibromothiophene?
+
The CAS number for 2,5-Dibromothiophene is 3141-27-3 and its empirical formula is C4H2Br2S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,5-Dibromothiophene in Vetec™ reagent grade with an assay of 94%. This product is not represented as USP, BP, EP or pharmaceutical grade.
What are the safety considerations when handling 2,5-Dibromothiophene?
+
2,5-Dibromothiophene is classified with the GHS symbol GHS07 and the signal word Warning. It carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Ensure proper ventilation and use appropriate personal protective equipment such as gloves, eye protection, and respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray.
How is 2,5-Dibromothiophene packed and exported?
+
2,5-Dibromothiophene is carefully packed to maintain its integrity during transit and is exported globally by Tech Serve Solutions, adhering to all necessary shipping regulations.
How can I request a quote or sample for 2,5-Dibromothiophene?
+
To request a quote or a sample of 2,5-Dibromothiophene, please use the enquiry form on our website or contact our sales team directly.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis