2-(4-Methoxyphenylcarbonothioylthio)ethanoic acid
2-(4-Methoxyphenylcarbonothioylthio)ethanoic acid (CAS: 38204-31-8; C10H10O3S2; MW: 242.31) is a dithiobenzoate compound widely employed as a Chain Transfer Agent (CTA) in Reversible Addition-Fragmentation chain Transfer (RAFT) polymerization. It facilitates controlled radical polymerization, particularly for methacrylate and methacrylamide monomers, enabling precise control over polymer architecture and molecular weight. This reagent is supplied by Tech Serve Solutions for advanced materials science and polymer research.
- IUPAC
- (4-Methoxybenzothioylthio)ethanoic acid,2-[(4-Methoxyphenylthioxomethyl)thio]ethanoic acid,CTA,RAFT dithiobenzoate

Controlled Radical Polymerization
Utilised as a RAFT agent, this compound enables controlled synthesis of polymers with defined molecular weights and narrow polydispersity. It is particularly effective for polymerizing methacrylate and methacrylamide monomers, offering enhanced control over polymer chain growth.
Polymer Architecture Design
The reagent's specific structure allows for the synthesis of polymers with complex architectures, such as block copolymers and star polymers. Its role as a CTA is crucial for achieving precise control over chain termination and initiation events.
Materials Science Research
Applied in the development of advanced polymeric materials for diverse applications. The controlled polymerization capabilities facilitated by this agent are vital for tailoring material properties for specific end-uses.
| Molecular weight | 242.31 |
|---|---|
| Empirical formula | C10H10O3S2 |
| Assay | ≥97% |
| Storage temperature | 2-8°C |
| Application | RAFT agent for controlled radical polymerization; especially suited for the polymerization of methacrylate and methacrylamide monomers. Chain Transfer Agent (CTA) with electron donating group to increase fragmentation and reduce polymerization time. |
| Melting point | 122-125 °C |

Hazard statements
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(4-Methoxyphenylcarbonothioylthio)ethanoic acid used for?
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This compound is used as a RAFT agent for controlled radical polymerization, particularly for methacrylate and methacrylamide monomers, allowing for precise control over polymer molecular weight and architecture.
What is the CAS number and molecular formula?
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The CAS number is 38204-31-8 and the molecular formula is C10H10O3S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97%. It is supplied for research and development purposes and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations?
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This compound is classified under GHS07 with a warning signal word. It may cause an allergic skin reaction (H317). Wear appropriate personal protective equipment, including gloves and protective clothing (P280), and handle in a well-ventilated area. Storage at 2-8°C is recommended.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports this chemical globally, adhering to all relevant international shipping regulations for chemical products.
How can I request a sample or quote?
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Please use the 'Request a Quote' or 'Request a Sample' button on our product page, or contact our sales team directly with your specific requirements.
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