5-Chloropyrimidine-2-thiol
5-Chloropyrimidine-2-thiol (CAS: 34772-97-9; Formula: C4H3ClN2S; Molar Mass: 146.60 g/mol) is a halogenated heterocyclic compound supplied by Tech Serve Solutions. This pyrimidine derivative serves as a valuable building block in organic synthesis, particularly for the construction of more complex molecular architectures. Its chemical structure, featuring both a chlorine atom and a thiol group on the pyrimidine ring, offers versatile reactivity for various chemical transformations and research applications.
- IUPAC
- 5-Chloro-2-mercaptopyrimidine
- Synonyms
- 5-Chloro-2-mercaptopyrimidine

Organic Synthesis Intermediate
Used as a key intermediate in the synthesis of novel organic compounds. The reactive chlorine and thiol functionalities allow for diverse derivatisation pathways in medicinal chemistry and materials science research.
Heterocyclic Chemistry Research
A useful building block for creating substituted pyrimidine derivatives. Its structure is amenable to nucleophilic substitution and other reactions critical for developing new chemical entities.
Pharmaceutical Research
Employed in the research and development of potential pharmaceutical agents, leveraging the pyrimidine core structure common in many biologically active molecules.
| Molecular weight | 146.60 |
|---|---|
| Empirical formula | C4H3ClN2S |
| Assay | 95% |
| Melting point | 210-225 °C |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloropyrimidine-2-thiol used for?
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5-Chloropyrimidine-2-thiol (CAS: 34772-97-9) is primarily used as a building block in organic synthesis and heterocyclic chemistry research, including in pharmaceutical research and development.
What is the CAS number and formula for 5-Chloropyrimidine-2-thiol?
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The CAS number is 34772-97-9 and the empirical formula is C4H3ClN2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Chloropyrimidine-2-thiol with a minimum assay of 95%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety considerations when handling 5-Chloropyrimidine-2-thiol?
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5-Chloropyrimidine-2-thiol is classified as Danger, with hazards H302 (Harmful if swallowed) and H318 (Causes serious eye damage). Appropriate personal protective equipment, including eye protection and gloves, should be worn. Ensure adequate ventilation and avoid ingestion and eye contact.
Can Tech Serve Solutions export 5-Chloropyrimidine-2-thiol?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 5-Chloropyrimidine-2-thiol, and can facilitate international shipments.
How can I request a sample or quote for 5-Chloropyrimidine-2-thiol?
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To request a sample or a quote for 5-Chloropyrimidine-2-thiol, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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