2′,4′-Difluoroacetophenone
2′,4′-Difluoroacetophenone (CAS: 364-83-0) is a fluorinated organic compound with the molecular formula F₂C₆H₃COCH₃ and a molecular weight of 156.13 g/mol. This ketone serves as a valuable building block in organic synthesis, particularly for the preparation of difluorinated chalcones and other complex fluorinated molecules. It is supplied by Tech Serve Solutions with a purity of 98%.
- Synonyms
- F2C6H3COCH3
Synthesis of Difluorinated Chalcones
2′,4′-Difluoroacetophenone is a key starting material for the synthesis of difluorinated chalcones. These compounds can be further utilised in various organic chemistry research and development projects.
Fluorinated Building Block
As a fluorinated aromatic ketone, it functions as a versatile building block in the synthesis of more complex organic molecules. Its structure allows for diverse chemical transformations.
Chemical Research Intermediate
This compound is employed in research laboratories for the development of novel organic compounds and the exploration of new synthetic methodologies involving fluorinated motifs.
| Molecular weight | 156.13 |
|---|---|
| Linear formula | F2C6H3COCH3 |
| Assay | 98% |
| Boiling point | 80-81 °C/25 mmHg(lit.) |
| Density | 1.234 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.488(lit.) |
| Application | 2′,4′-Difluoroacetophenone has been used as starting reagent in the synthesis of difluorinated chalcones1. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,4′-Difluoroacetophenone used for?
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2′,4′-Difluoroacetophenone is used as a starting reagent in the synthesis of difluorinated chalcones and as a general building block in organic synthesis, particularly for creating fluorinated molecules.
What is the CAS number and molecular formula for 2′,4′-Difluoroacetophenone?
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The CAS number is 364-83-0 and the molecular formula is F₂C₆H₃COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′,4′-Difluoroacetophenone with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2′,4′-Difluoroacetophenone be handled safely?
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2′,4′-Difluoroacetophenone is a Warning substance (GHS07) with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Handle with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Store in a well-ventilated place.
Is 2′,4′-Difluoroacetophenone packed and shipped internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2′,4′-Difluoroacetophenone.
How can I request a quote or sample for 2′,4′-Difluoroacetophenone?
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To request a quote or sample for 2′,4′-Difluoroacetophenone, please contact our sales department via the website or your dedicated account manager.
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