2′,4′-Dichloro-5′-fluoroacetophenone
2′,4′-Dichloro-5′-fluoroacetophenone (CAS 704-10-9) is a fluorinated organic building block with the molecular formula Cl2C6H2(F)COCH3 and a molecular weight of 207.03 g/mol. This compound is a key intermediate in the synthesis of various pharmaceutical agents, particularly fluoroquinolone antibiotics and other heterocyclic antibacterial compounds. It is supplied by Tech Serve Solutions with an assay of 90%.
- Synonyms
- Cl2C6H2(F)COCH3
Fluoroquinolone Synthesis
This compound serves as a crucial intermediate in the multi-step synthesis of fluoroquinolone antibiotics, a class of broad-spectrum antibacterial drugs. Its specific structural features enable the introduction of necessary functional groups for effective antimicrobial activity.
Heterocyclic Antibacterial Agents
Beyond fluoroquinolones, 2′,4′-Dichloro-5′-fluoroacetophenone is utilised in the development of other novel heterocyclic compounds with potential antibacterial properties. Research into new antimicrobial scaffolds often employs such fluorinated building blocks.
Organic Synthesis Building Block
As a versatile organic building block, this acetophenone derivative is valuable in general organic synthesis. It allows for further functionalisation and incorporation into complex molecular architectures for diverse research and development purposes.
| Molecular weight | 207.03 |
|---|---|
| Linear formula | Cl2C6H2(F)COCH3 |
| Assay | 90% |
| Boiling point | 167 °C(lit.) |
| Density | 1.425 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.546(lit.) |
| Application | A versatile intermediate used in the synthesis of fluoroquinolone1,2 and other heterocyclic antibacterials.3,4 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,4′-Dichloro-5′-fluoroacetophenone used for?
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2′,4′-Dichloro-5′-fluoroacetophenone is primarily used as a versatile intermediate in the synthesis of fluoroquinolone and other heterocyclic antibacterial agents. It also functions as a general organic building block in chemical synthesis.
What is the CAS number and chemical formula for 2′,4′-Dichloro-5′-fluoroacetophenone?
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The CAS number is 704-10-9, and the linear chemical formula is Cl2C6H2(F)COCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′,4′-Dichloro-5′-fluoroacetophenone with a minimum assay of 90%. This product is not classified as USP, BP, or EP grade and is intended for research and laboratory use.
How should 2′,4′-Dichloro-5′-fluoroacetophenone be handled?
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This compound is classified as a Warning with hazards including skin irritation (H315), eye irritation (H319), and respiratory tract irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
How is this chemical packed, shipped, and exported?
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2′,4′-Dichloro-5′-fluoroacetophenone is carefully packed according to international shipping regulations to ensure safe transit. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or a quote for 2′,4′-Dichloro-5′-fluoroacetophenone?
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To request a sample or obtain a quotation, please contact our sales team through the website or by calling our office. Please specify the required quantity and your shipping destination.
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