2′,4′-Dichloroacetophenone
2′,4′-Dichloroacetophenone (CAS 2234-16-4) is a halogenated aromatic ketone with the molecular formula C8H6Cl2O and a molecular weight of 189.04 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the preparation of various chemical intermediates. It is characterized by its ketone functional group and dichloro-substituted phenyl ring, enabling diverse chemical transformations. Tech Serve Solutions supplies this reagent for research and development purposes.
- Synonyms
- Cl2C6H3COCH3

Organic Synthesis Intermediate
2′,4′-Dichloroacetophenone is utilized as a key intermediate in the synthesis of more complex organic molecules. Its reactive carbonyl group and halogen substituents allow for a range of chemical modifications and coupling reactions.
Schiff Base Derivative Synthesis
This compound has been employed in the preparation of Schiff base derivatives. These derivatives are often investigated for their potential biological activities and applications in coordination chemistry.
Research and Development
As a versatile building block, 2′,4′-Dichloroacetophenone is supplied for use in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities.
| Molecular weight | 189.04 |
|---|---|
| Linear formula | Cl2C6H3COCH3 |
| Assay | 96% |
| Boiling point | 140-150 °C/15 mmHg(lit.) |
| Refractive index | n20/D 1.5635(lit.) |
| Application | 2′,4′-Dichloroacetophenone was used in the synthesis of the Schiff base derivatives1. |
| Melting point | 33-34 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41-52/53 |
| Safety statements (S) | 26-39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′,4′-Dichloroacetophenone used for?
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2′,4′-Dichloroacetophenone is primarily used as a building block in organic synthesis, including the preparation of Schiff base derivatives. It is suitable for research and development applications.
What is the CAS number and chemical formula for 2′,4′-Dichloroacetophenone?
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The CAS number for 2′,4′-Dichloroacetophenone is 2234-16-4, and its linear formula is Cl₂C₆H₃COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′,4′-Dichloroacetophenone with an assay of 96%. This product is intended for research and technical use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 2′,4′-Dichloroacetophenone be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (N95 US), eyeshields, and gloves. It is classified as harmful if swallowed and causes serious eye damage (H302-H318). Avoid contact with eyes and skin, and ensure adequate ventilation.
Is 2′,4′-Dichloroacetophenone packed and shipped internationally?
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Yes, Tech Serve Solutions exports and ships fine chemicals globally. Specific packaging and shipping details can be provided upon request.
How can I request a sample or quote for 2′,4′-Dichloroacetophenone?
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To request a sample or a quotation, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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