2,4,6-Trimethylphenol
2,4,6-Trimethylphenol (CAS: 527-60-6) is a phenolic organic compound with the linear formula (CH3)3C6H2OH and a molecular weight of 136.19 g/mol. This solid compound, often referred to as Mesitol, is primarily utilised as a chemical intermediate and building block in organic synthesis. Its structure, featuring a hydroxyl group attached to a benzene ring with three methyl substituents, makes it a valuable precursor in the development of more complex molecules.
- IUPAC
- Mesitol
- Synonyms
- 527-60-6(CH3)3C6H2OHMesitol

Organic Synthesis Intermediate
2,4,6-Trimethylphenol serves as a key intermediate in the synthesis of various organic compounds. Its reactive hydroxyl group and sterically hindered aromatic ring allow for specific chemical transformations in the creation of fine chemicals and specialised materials.
Building Block in Research
As an organic building block, this compound is employed in academic and industrial research laboratories for the development of novel molecules and materials. Its defined structure is useful in studies involving phenolic derivatives and their reactivity.
Precursor for Antioxidants
Derivatives of sterically hindered phenols, such as 2,4,6-Trimethylphenol, can be synthesised into effective antioxidants. These compounds are important for stabilising polymers, fuels, and lubricants against oxidative degradation.
| Molecular weight | 136.19 |
|---|---|
| Linear formula | (CH3)3C6H2OH |
| Assay | 97% |
| Boiling point | 220 °C(lit.) |
| Melting point | 70-72 °C(lit.)71-74 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Transport (UN / ADR) | UN 2430 8 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,6-Trimethylphenol used for?
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2,4,6-Trimethylphenol is primarily used as an intermediate in organic synthesis and as a building block in chemical research. It can also serve as a precursor for antioxidants.
What is the CAS number and formula for 2,4,6-Trimethylphenol?
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The CAS number for 2,4,6-Trimethylphenol is 527-60-6 and its linear formula is (CH3)3C6H2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4,6-Trimethylphenol with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 2,4,6-Trimethylphenol be handled?
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2,4,6-Trimethylphenol is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 filters), is essential during handling. Ensure adequate ventilation and follow emergency procedures (P280-P305 + P351 + P338-P310).
Is 2,4,6-Trimethylphenol a controlled substance?
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The provided data does not indicate that 2,4,6-Trimethylphenol is a controlled substance.
How is 2,4,6-Trimethylphenol packed and exported?
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2,4,6-Trimethylphenol is packed according to UN 2430 8 / PGIII regulations for safe transport and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or sample of 2,4,6-Trimethylphenol, please contact our sales team through the website or by phone.
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