2,4,6-Tri-tert-butylpyrimidine
2,4,6-Tri-tert-butylpyrimidine (CAS 67490-21-5) is a sterically hindered pyrimidine derivative with the molecular formula C16H28N2 and a molecular weight of 248.41 g/mol. This organic compound serves as a versatile building block in chemical synthesis, particularly within heterocyclic chemistry. Its unique structure lends itself to various applications where controlled reactivity and specific molecular architecture are desired, contributing to the development of novel materials and complex organic molecules.
- Synonyms
- 67490-21-5

Heterocyclic Synthesis Intermediate
Utilised as a foundational component in the synthesis of complex heterocyclic compounds. Its substituted pyrimidine core offers a platform for further chemical modifications and elaborations.
Organic Synthesis Building Block
A key intermediate in organic chemistry for constructing larger, more intricate molecular structures. The tert-butyl groups provide steric bulk, influencing reaction pathways and product selectivity.
Research and Development
Essential for academic and industrial research exploring new chemical entities and reaction methodologies. Enables the investigation of pyrimidine-based compounds in various scientific fields.
| Molecular weight | 248.41 |
|---|---|
| Empirical formula | C16H28N2 |
| Assay | 97% |
| Melting point | 77-80 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,6-Tri-tert-butylpyrimidine used for?
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2,4,6-Tri-tert-butylpyrimidine is primarily used as a building block and intermediate in organic synthesis, particularly for creating complex heterocyclic compounds and in research and development.
What is the CAS number and formula for 2,4,6-Tri-tert-butylpyrimidine?
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The CAS number is 67490-21-5 and the empirical formula is C16H28N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4,6-Tri-tert-butylpyrimidine with an assay of 97%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP.
How should 2,4,6-Tri-tert-butylpyrimidine be handled?
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Handle 2,4,6-Tri-tert-butylpyrimidine with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
Can Tech Serve Solutions export 2,4,6-Tri-tert-butylpyrimidine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,4,6-Tri-tert-butylpyrimidine.
How can I request a quote or sample?
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To request a quote or sample of 2,4,6-Tri-tert-butylpyrimidine, please contact our sales team through the website or by phone.
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