6,9-Dichloro-2-methoxyacridine
6,9-Dichloro-2-methoxyacridine (CAS 86-38-4) is a halogenated heterocyclic compound with the molecular formula C14H9Cl2NO and a molecular weight of 278.13 g/mol. It serves as a valuable building block in organic synthesis, particularly for the development of novel acridine derivatives. Its defined chemical structure and reactivity make it suitable for research and development applications in medicinal chemistry and materials science, contributing to the synthesis of complex molecular architectures.
- Synonyms
- C14H9Cl2NO

Synthesis of 9-Amino-6-chloro-2-methoxyacridine
This compound has been employed in the synthesis of 9-amino-6-chloro-2-methoxyacridine, a derivative with potential applications in various chemical research fields. The reaction pathway leverages the specific substitution pattern of the starting material.
Preparation of N'-Substituted Acridines
6,9-Dichloro-2-methoxyacridine is a precursor for creating N'-substituted acridine derivatives, such as N'-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine. These syntheses are key for exploring structure-activity relationships in medicinal chemistry.
Diamine-Linked Acridine Synthesis
It is utilised in the synthesis of diamine-linked acridine compounds, exemplified by N,N'-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine. This application highlights its role in constructing more complex molecules for research purposes.
| Molecular weight | 278.13 |
|---|---|
| Empirical formula | C14H9Cl2NO |
| Assay | 97% |
| Application | 6,9-Dichloro-2-methoxyacridine was used in the synthesis of 9-amino-6-chloro-2-methoxyacridine1, N′-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine2 and N,N′-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine2. |
| Melting point | 163-165 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6,9-Dichloro-2-methoxyacridine used for?
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6,9-Dichloro-2-methoxyacridine is primarily used as a building block in organic synthesis for the preparation of various acridine derivatives, including amine-substituted and diamine-linked acridines.
What are the CAS number and formula for 6,9-Dichloro-2-methoxyacridine?
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The CAS number for 6,9-Dichloro-2-methoxyacridine is 86-38-4, and its molecular formula is C14H9Cl2NO. The empirical formula listed in the data is C14H9Cl2NO, with a molecular weight of 278.13 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6,9-Dichloro-2-methoxyacridine with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 6,9-Dichloro-2-methoxyacridine be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves. It is classified as a danger with hazards including skin irritation (H315), skin sensitisation (H317), eye irritation (H319), respiratory sensitisation (H334), and respiratory irritation (H335). Ensure adequate ventilation and avoid breathing dust.
Is 6,9-Dichloro-2-methoxyacridine a controlled substance?
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The provided data does not indicate that 6,9-Dichloro-2-methoxyacridine is a controlled substance.
How is 6,9-Dichloro-2-methoxyacridine packed and exported?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging for international shipment in compliance with all relevant regulations. Specific packaging details can be provided upon request.
How can I request a sample or quote for 6,9-Dichloro-2-methoxyacridine?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through the website or by direct inquiry, referencing the product name and CAS number 86-38-4.
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