2,4,5-Trifluorobenzoic acid
2,4,5-Trifluorobenzoic acid (CAS 446-17-3) is a fluorinated aromatic carboxylic acid with a molecular weight of 176.09 g/mol. This compound serves as a valuable building block in organic synthesis. Its trifluorinated phenyl ring and carboxylic acid functionality make it useful for introducing specific structural motifs into more complex molecules, particularly within the fields of medicinal chemistry and materials science. It is typically supplied at a high purity for research and development applications.
- Synonyms
- 446-17-3F3C6H2CO2H

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. The presence of three fluorine atoms and a carboxylic acid group offers versatile reaction possibilities for chemists.
Pharmaceutical Research
A valuable building block for the development of novel pharmaceutical agents. Fluorinated compounds are often investigated for their enhanced metabolic stability and binding affinities in drug discovery.
Materials Science
Incorporated into the design and synthesis of advanced materials. The unique electronic properties conferred by fluorine atoms can influence material characteristics.
| Molecular weight | 176.09 |
|---|---|
| Linear formula | F3C6H2CO2H |
| Assay | 99% |
| Melting point | 94-96 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,5-Trifluorobenzoic acid used for?
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2,4,5-Trifluorobenzoic acid is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and materials science for the development of new compounds.
What is the CAS number and formula for 2,4,5-Trifluorobenzoic acid?
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The CAS number is 446-17-3 and the linear formula is F₃C₆H₂CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies 2,4,5-Trifluorobenzoic acid with an assay of 99%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should 2,4,5-Trifluorobenzoic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified as an irritant to the skin, eyes, and respiratory tract.
How is 2,4,5-Trifluorobenzoic acid packed and shipped?
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2,4,5-Trifluorobenzoic acid is carefully packed to ensure safe transit and is available for export worldwide by Tech Serve Solutions.
How can I request a sample or quote for 2,4,5-Trifluorobenzoic acid?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or direct contact details.
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