2,3,6-Trifluorobenzyl bromide
2,3,6-Trifluorobenzyl bromide (CAS: 151412-02-1) is a fluorinated aryl building block with the linear formula F 3 C 6 H 2 CH 2 Br and a molecular weight of 225.01 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly for introducing the 2,3,6-trifluorobenzyl moiety into larger molecular structures. Its applications span diverse areas of chemical research and development.
- Synonyms
- 151412-02-1F3C6H2CH2Br
Organic Synthesis Intermediate
Serves as a key reagent in the synthesis of complex organic molecules. It is employed to introduce the 2,3,6-trifluorobenzyl group, which is often incorporated into pharmaceuticals and agrochemicals.
Fluorinated Building Block
As a fluorinated aryl compound, it is utilised in the construction of novel materials and advanced chemical entities where fluorine substitution is desired for altered chemical and physical properties.
Pharmaceutical Research
Used in the discovery and development of new drug candidates. The trifluorobenzyl group can influence pharmacokinetic properties such as metabolic stability and lipophilicity.
| Molecular weight | 225.01 |
|---|---|
| Linear formula | F3C6H2CH2Br |
| Assay | 97% |
| Boiling point | 114 °C(lit.) |
| Density | 1.718 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5074(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,6-Trifluorobenzyl bromide used for?
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2,3,6-Trifluorobenzyl bromide is primarily used as an intermediate in organic synthesis, particularly for introducing the 2,3,6-trifluorobenzyl moiety into target molecules for pharmaceutical and agrochemical research and development.
What is the CAS number and formula for 2,3,6-Trifluorobenzyl bromide?
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The CAS number is 151412-02-1, and its linear formula is F 3 C 6 H 2 CH 2 Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,6-Trifluorobenzyl bromide with an assay of 97%. This is a research-grade chemical and TSS does not represent it as USP, BP, or EP.
How should 2,3,6-Trifluorobenzyl bromide be handled safely?
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2,3,6-Trifluorobenzyl bromide is a Danger hazard (GHS05, H314), causing severe skin burns and eye damage. Handle with extreme caution, wearing full protective equipment including gloves, goggles, a face shield, and appropriate respiratory protection. Refer to the Safety Data Sheet for detailed handling instructions.
How is 2,3,6-Trifluorobenzyl bromide packed and exported?
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2,3,6-Trifluorobenzyl bromide is packed according to international shipping regulations for hazardous materials, including its classification as UN 3265, Class 8, Packing Group II. TSS exports this chemical globally, adhering to all relevant transport and customs requirements.
How can I request a quote or sample for 2,3,6-Trifluorobenzyl bromide?
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To request a quote or a sample of 2,3,6-Trifluorobenzyl bromide, please contact the Tech Serve Solutions sales department via the website or by phone, providing your contact details and the required quantity.
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