2,3,5-Trifluoropyridine-4-carboxylic acid
2,3,5-Trifluoropyridine-4-carboxylic acid (CAS: 675602-91-2) is a fluorinated heterocyclic building block with the molecular formula C6H2F3NO2 and a molecular weight of 177.08 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. Its trifluoropyridine structure offers unique reactivity for constructing complex molecular architectures. Tech Serve Solutions supplies this reagent at a minimum assay of 97% for research and development purposes.
- IUPAC
- 2,3,5-Trifluoroisonicotinic acid
- Synonyms
- 675602-91-2, C6H2F3NO2, 2,3,5-Trifluoroisonicotinic acid

Pharmaceutical Intermediate
Utilised in the synthesis of novel drug candidates, where the trifluoropyridine moiety can impart desirable pharmacokinetic properties. Its structure allows for diverse derivatisation in medicinal chemistry programmes.
Agrochemical Development
Serves as a key building block for the creation of new pesticides and herbicides. The presence of fluorine atoms can enhance the biological activity and stability of agrochemical agents.
Materials Science
Incorporated into the synthesis of specialised polymers and functional materials, leveraging the unique electronic and physical properties conferred by the fluorinated pyridine ring.
Organic Synthesis
A versatile reagent for constructing complex fluorinated heterocyclic compounds. Its carboxylic acid group provides a handle for various coupling and functionalisation reactions.
| Molecular weight | 177.08 |
|---|---|
| Empirical formula | C6H2F3NO2 |
| Assay | 97% |
| Melting point | 106-111 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,5-Trifluoropyridine-4-carboxylic acid primarily used for?
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2,3,5-Trifluoropyridine-4-carboxylic acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals, and in materials science.
What is the CAS number and molecular formula?
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The CAS number is 675602-91-2, and the molecular formula is C6H2F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum assay of 97%. It is supplied for research and development and is not represented as USP, BP, or EP grade.
How should 2,3,5-Trifluoropyridine-4-carboxylic acid be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust. Ensure good ventilation. This compound is classified as an irritant to skin, eyes, and the respiratory tract (H315-H319-H335).
How is this chemical packed and shipped?
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This chemical is carefully packed and exported according to international shipping regulations for chemical reagents, ensuring safe transit.
How can I request a sample or quote?
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To request a sample or a quote, please use the 'Request Quote' or 'Sample Request' functionality on our website, or contact our sales team directly.
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