2,3,4,5,6-Pentafluoroaniline
2,3,4,5,6-Pentafluoroaniline (CAS: 771-60-8; C6F5NH2) is a fluorinated aromatic amine supplied by Tech Serve Solutions. With a molecular weight of 183.08 g/mol, this compound is primarily utilised as a building block in organic synthesis. Its structure makes it valuable for introducing the pentafluorophenyl moiety into various molecules, finding applications in the development of catalysts and specialised chemical intermediates.
- Synonyms
- 5,6-PentafluoroanilineC6F5NH2771-60-8

Catalyst Precursor
2,3,4,5,6-Pentafluoroaniline can be used in the preparation of pentafluorophenylammonium triflate, an effective catalyst for esterification and thioesterification reactions.
Synthesis of Titanium Complexes
This compound has been employed in the synthesis of various titanium complexes featuring bidentate salicylaldiminato ligands.
Fluorinated Building Block
As an aryl fluorinated building block, it serves as a key intermediate for introducing fluorinated aromatic structures into more complex organic molecules.
| Molecular weight | 183.08 |
|---|---|
| Linear formula | C6F5NH2 |
| Assay | 99% |
| Boiling point | 153 °C(lit.) |
| Solubility | toluene: soluble |
| Application | 2,3,4,5,6-Pentafluoroaniline may be used in the preparation of pentafluorophenylammonium triflate, an efficient catalyst for esterification and thioesterification1. 2,3,4,5,6-Pentafluoroaniline was used in synthesis of various titanium complexes having two anionic [N, O–] bidentate salicylaldiminato ligands2. |
| Melting point | 33-35 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4,5,6-Pentafluoroaniline used for?
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2,3,4,5,6-Pentafluoroaniline is primarily used as a building block in organic synthesis, for example, in the preparation of catalysts and specialised chemical intermediates, including titanium complexes.
What are the CAS number and chemical formula for 2,3,4,5,6-Pentafluoroaniline?
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The CAS number is 771-60-8, and the linear chemical formula is C6F5NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3,4,5,6-Pentafluoroaniline with a minimum assay of 99%. We do not represent this product as USP, BP, EP or other pharmacopoeial grades.
How should 2,3,4,5,6-Pentafluoroaniline be handled?
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2,3,4,5,6-Pentafluoroaniline is a warning chemical that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including dust mask type N95, eyeshields, and gloves, should be used during handling.
Is 2,3,4,5,6-Pentafluoroaniline packed and exported by TSS?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,3,4,5,6-Pentafluoroaniline.
How can I request a quote or sample of 2,3,4,5,6-Pentafluoroaniline?
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To request a quote or sample, please contact our sales team through the website or by phone. Specify the product name and CAS number (771-60-8).
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