2,2′-Dithiodiethanol
2,2′-Dithiodiethanol (CAS: 1892-29-1), also known as Bis(2-hydroxyethyl) disulfide, is an organic sulfur compound with the linear formula HOCH2CH2SSCH2CH2OH and a molecular weight of 154.25 g/mol. This chemical serves as a valuable building block in organic synthesis and finds application in the preparation of various sulfur-containing compounds. Its unique disulfide linkage and hydroxyl functional groups make it a versatile intermediate for chemical research and development.
- IUPAC
- Bis(2-hydroxyethyl) disulfide
- Synonyms
- Bis(2-hydroxyethyl) disulfideEthanediol, 2,2'-dithio-2,2'-Dithiodi-ethanol

Organic Synthesis Intermediate
2,2′-Dithiodiethanol is utilized as a versatile building block in the synthesis of more complex organic molecules. Its reactive disulfide bond and terminal hydroxyl groups allow for diverse chemical transformations.
Preparation of Sulfur Compounds
This compound is employed in the creation of specialty sulfur-containing chemicals. It can be used to introduce the disulfide moiety into various molecular structures for research purposes.
Chemical Research and Development
Primarily used in R&D settings, 2,2′-Dithiodiethanol serves as a reagent for exploring new chemical reactions and developing novel materials or compounds with specific sulfur functionalities.
| Molecular weight | 154.25 |
|---|---|
| Linear formula | HOCH2CH2SSCH2CH2OH |
| Assay | ~90% (GC) |
| Boiling point | 158-163 °C/3.5 mmHg(lit.) |
| Density | 1.29 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.567 |
| Melting point | 25-27 °C(lit.) |


Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-41 |
| Safety statements (S) | 26-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2′-Dithiodiethanol used for?
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2,2′-Dithiodiethanol is primarily used as a building block in organic synthesis and for the preparation of various sulfur compounds in chemical research and development.
What are the CAS number and formula for 2,2′-Dithiodiethanol?
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The CAS number for 2,2′-Dithiodiethanol is 1892-29-1, and its linear formula is HOCH2CH2SSCH2CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2′-Dithiodiethanol with an assay of approximately 90% (GC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,2′-Dithiodiethanol be handled safely?
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2,2′-Dithiodiethanol is a dangerous substance. It is toxic if swallowed (H301) and causes serious eye damage (H318). Handle with extreme care, using appropriate personal protective equipment including eyeshields, face shields, gloves, and a suitable respirator.
How is 2,2′-Dithiodiethanol packed, shipped, and exported?
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2,2′-Dithiodiethanol is packed and shipped according to international regulations for hazardous materials. As a specialist global supplier, TSS manages the export of this chemical to various international destinations.
How can I request a quote or sample for 2,2′-Dithiodiethanol?
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To request a quote or a sample of 2,2′-Dithiodiethanol, please contact our sales department via the website or by phone, providing your specific requirements and shipping details.
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