2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane
2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane (CAS 131833-92-6) is a chiral bisoxazoline ligand with a molecular weight of 266.38 g/mol. This compound serves as a valuable chiral catalyst in asymmetric synthesis, facilitating the stereoselective formation of complex molecules. Its specific structure makes it a privileged ligand, widely employed in various chemical synthesis applications requiring high enantiomeric control.
- IUPAC
- S-4,5-Dihydro-2-(2-((S)-4,5-dihydro-4-isopropyloxazol-2-yl)propan-2-yl)-4-isopropyloxazole
- Synonyms
- C15H26N2O2S-4,5-Dihydro-2-(2-((S)-4,5-dihydro-4-isopropyloxazol-2-yl)propan-2-yl)-4-isopropyloxazole

Chiral Catalyst in Asymmetric Synthesis
This bisoxazoline ligand acts as a potent chiral catalyst for asymmetric synthesis. It is instrumental in reactions where precise stereochemical control is paramount, enabling the formation of enantiomerically enriched products.
Privileged Ligand for Stereoselective Reactions
The unique structural features of 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane classify it as a privileged ligand. It is frequently utilised in various catalytic systems to direct stereoselective transformations in organic chemistry.
Reagent in Chemical Synthesis
As a key component in advanced chemical synthesis, this compound aids researchers and manufacturers in developing novel chiral compounds and intermediates for pharmaceuticals and fine chemicals.
| Molecular weight | 266.38 |
|---|---|
| Empirical formula | C15H26N2O2 |
| Assay | 96% |
| Density | 0.9864 g/mL at 25 °C |
| Refractive index | n20/D 1.4665 |
| Optical activity | [α]/D -121 to -113°, c = 1% in chloroform |
| Application | Bisoxazoline ligand - chiral catalyst for asymetric synthesis.1 |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane used for?
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2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane is primarily used as a chiral bisoxazoline ligand and catalyst in asymmetric synthesis, enabling stereoselective formation of complex molecules. It is also employed as a privileged ligand in various chemical synthesis applications.
What is the CAS number and molecular formula for 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane?
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The CAS number for 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane is 131833-92-6. Its empirical formula is C15H26N2O2, with a molecular weight of 266.38 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane with an assay of 96%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane be handled safely?
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This compound is classified as a Warning. It causes serious eye irritation (H319). Ensure adequate ventilation, wear safety goggles, gloves, and appropriate respiratory protection (e.g., type ABEK respirator filter) when handling. In case of contact with eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane?
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To request a sample or a quotation for 2,2-Bis((4S)-(–)-4-isopropyloxazoline)propane, please contact our sales team through the website or designated contact channels.
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