2,2-Bis(hydroxymethyl)propionic acid
2,2-Bis(hydroxymethyl)propionic acid (CAS: 4767-03-7) is a versatile organic compound with the molecular formula (HOCH2)2C(CH3)COOH and a molecular weight of 134.13 g/mol. This white crystalline solid functions as a key building block in organic synthesis. Its structure, featuring two primary hydroxyl groups and a carboxylic acid moiety, makes it valuable for creating complex molecules, particularly in the development of polymers and dendrimers for advanced applications.
- IUPAC
- Bis-MPA,DMPA®,Dimethylolpropionic acid
- Synonyms
- (HOCH2)2C(CH3)COOHBis-MPADMPA®Dimethylolpropionic acid
Polyurethane Dispersions
2,2-Bis(hydroxymethyl)propionic acid is utilised in the synthesis and characterisation of polyurethane dispersions, often modified with siloxanes and incorporated with clays for enhanced material properties.
Dendrimer Synthesis
This compound serves as a precursor for dendrimers with potent applications in drug delivery systems, including anticancer agents like cisplatin and doxorubicin, and in specialised therapies such as boron neutron capture and photodynamic therapy.
Organic Synthesis Building Block
As a functionalised carboxylic acid, it is an important intermediate in the synthesis of various organic compounds, contributing to the development of fine chemicals and novel materials.
| Molecular weight | 134.13 |
|---|---|
| Linear formula | (HOCH2)2C(CH3)COOH |
| Assay | 98% |
| Solubility | H2O: solubleacetone: slightly solublebenzene: insolublemethanol: soluble |
| Vapour density | <1 (vs air) |
| Application | 2,2-Bis(hydroxymethyl)propionic acid was used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays1.2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy2. |
| Melting point | 189-191 °C(lit.) |
Hazard statements
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2-Bis(hydroxymethyl)propionic acid used for?
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2,2-Bis(hydroxymethyl)propionic acid is used as a building block in organic synthesis, notably in the creation of polyurethane dispersions and dendrimers for advanced applications including drug delivery and specialised therapies.
What is the CAS number and formula for 2,2-Bis(hydroxymethyl)propionic acid?
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The CAS number is 4767-03-7 and the linear formula is (HOCH2)2C(CH3)COOH.
What grade and purity does Tech Serve Solutions supply for 2,2-Bis(hydroxymethyl)propionic acid?
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Tech Serve Solutions supplies 2,2-Bis(hydroxymethyl)propionic acid with a purity of 98%. We do not represent this product as USP, BP, or EP grade unless explicitly stated otherwise in the product documentation.
How should 2,2-Bis(hydroxymethyl)propionic acid be handled safely?
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According to GHS classification, 2,2-Bis(hydroxymethyl)propionic acid is a warning substance, causing serious eye irritation (H319) and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment including eyeshields, gloves, and a type N95 dust mask. Ensure good ventilation.
Is 2,2-Bis(hydroxymethyl)propionic acid a controlled substance?
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Based on the provided data, 2,2-Bis(hydroxymethyl)propionic acid is not listed as a controlled substance. Its hazard classification is Xi (Irritant).
How is 2,2-Bis(hydroxymethyl)propionic acid packed and exported?
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2,2-Bis(hydroxymethyl)propionic acid is typically supplied in standard laboratory packaging suitable for export. Specific packing requirements can be discussed upon request.
How can I request a quote or sample for 2,2-Bis(hydroxymethyl)propionic acid?
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To request a quote or a sample of 2,2-Bis(hydroxymethyl)propionic acid, please contact the Tech Serve Solutions sales team via our website or listed contact details.
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