2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-4-pyridineboronic acid pinacol ester
2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-4-pyridineboronic acid pinacol ester (CAS: 1257651-11-8; C15H28BNO2) is a heteroaryl boronate ester with a molecular weight of 265.20 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its robust structure makes it suitable for constructing complex molecular architectures in research and development settings.
- IUPAC
- (2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyridin-4-yl)boronic acid pinacol ester
- Synonyms
- 6-Tetramethyl-1,2,3,6-tetrahydro-4-pyridineboronic acid pinacol ester1257651-11-8C15H28BNO2(2,2,6,6-Tetramethyl-3,6-dihydro-2H-pyridin-4-yl)boronic acid pinacol ester

Organic Synthesis Intermediate
This boronate ester is a key intermediate in various organic transformations, including Suzuki-Miyaura cross-coupling reactions. It enables the introduction of the tetrahydropyridine moiety into target molecules.
Pharmaceutical Research
Utilised in the development of novel pharmaceutical agents, this compound can be incorporated into lead structures for drug discovery programs. Its specific structural features may impart desirable pharmacokinetic properties.
Materials Science
May find application in the synthesis of novel materials where the pyridine ring and boronate ester functionality are leveraged for specific electronic or structural properties.
| Molecular weight | 265.20 |
|---|---|
| Empirical formula | C15H28BNO2 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 95-100 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,6,6-Tetramethyl-1,2,3,6-tetrahydro-4-pyridineboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly for cross-coupling reactions like the Suzuki-Miyaura coupling, and in pharmaceutical research and development.
What are the CAS number and molecular formula?
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The CAS number is 1257651-11-8 and the molecular formula is C15H28BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should this chemical be handled safely?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for detailed handling procedures.
How is this product packed and shipped?
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Products are carefully packed according to international shipping regulations to ensure safe transit. Tech Serve Solutions exports fine chemicals globally.
How can I request a sample or quote?
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To request a sample or a quotation, please visit the product page on the Tech Serve Solutions website and use the designated contact form or email the sales department.
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