2,2,6,6-Tetramethyl-4-(methylsulfonyloxy)-1-piperidinooxy, free radical
2,2,6,6-Tetramethyl-4-(methylsulfonyloxy)-1-piperidinooxy, free radical (CAS 35203-66-8, C10H20NO4S) is a stable nitroxide radical. With a molecular weight of 250.34 g/mol, it serves as a valuable reagent in organic synthesis. Its unique radical character makes it useful in applications involving controlled radical polymerisation, oxidation reactions, and as a spin label in research settings. TSS supplies this compound for various chemical research and development purposes.
- Synonyms
- 6-Tetramethyl-4-(methylsulfonyloxy)-1-piperidinooxy, free radical35203-66-8C10H20NO4S

Organic Synthesis
Utilised as a synthetic reagent in various organic transformations due to its stable radical nature. It can participate in oxidation reactions and mediate radical processes.
Radical Chemistry
A key compound for studies and applications in radical chemistry, including controlled radical polymerisation techniques. Its predictable reactivity is advantageous in mechanistic investigations.
TEMPO Derivatives
Serves as a derivative of TEMPO, offering similar radical stabilising properties with potential for tailored reactivity in specific synthetic pathways.
Spin Labelling
Can be employed as a spin label in various research contexts, particularly in electron paramagnetic resonance (EPR) spectroscopy, to study molecular dynamics and environments.
| Molecular weight | 250.34 |
|---|---|
| Empirical formula | C10H20NO4S |
| Assay | 98% |
| Melting point | 90-92 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,6,6-Tetramethyl-4-(methylsulfonyloxy)-1-piperidinooxy, free radical used for?
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This compound is primarily used in organic synthesis, radical chemistry, as a TEMPO derivative, and for spin labelling applications in research.
What are the CAS number and chemical formula for this product?
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The CAS number is 35203-66-8 and the empirical formula is C10H20NO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 98%. This is suitable for research and general synthetic purposes. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2,2,6,6-Tetramethyl-4-(methylsulfonyloxy)-1-piperidinooxy, free radical be handled?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Avoid inhalation of dust and contact with skin and eyes. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling instructions.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including this product.
How can I request a sample or quote?
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To request a sample or quote for 2,2,6,6-Tetramethyl-4-(methylsulfonyloxy)-1-piperidinooxy, free radical, please contact our sales team through the website or by phone.
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