2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester
2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester (CAS: 957198-31-1; Formula: C15H24BN3O2; MW: 289.18) is a specialized organometallic reagent. This boronate ester derivative is primarily utilized in organic synthesis, particularly for cross-coupling reactions. Its structural features make it a valuable building block for constructing complex molecules in pharmaceutical research and fine chemical synthesis, offering a reliable route to introduce the piperazinyl-pyridine moiety.
- IUPAC
- 2-(1-Piperazinyl)-4-pyridineboronic acid pinacol ester
Suzuki-Miyaura Cross-Coupling Reactions
This compound serves as an effective coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds. It facilitates the introduction of the 2-(1-piperazinyl)pyridine fragment into various organic scaffolds.
Pharmaceutical Intermediate Synthesis
Its utility extends to the synthesis of novel pharmaceutical agents. The piperazinyl-pyridine motif is present in several biologically active compounds, making this boronate ester a key intermediate in drug discovery programs.
Organic Synthesis Building Block
As a functionalised boronate ester, it is a versatile building block for a wide range of organic transformations. Researchers can leverage its reactivity to create diverse molecular architectures.
| Molecular weight | 289.18 |
|---|---|
| Empirical formula | C15H24BN3O2 |
| Assay | 97% |
| Melting point | 112-116 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, especially for Suzuki-Miyaura cross-coupling reactions and in the synthesis of pharmaceutical intermediates.
What are the CAS number and formula for this product?
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The CAS number is 957198-31-1 and the empirical formula is C15H24BN3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. This is a research-grade material, and we do not represent it as meeting USP, BP, or EP pharmacopoeial standards.
How should this chemical be handled safely?
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This product causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves, in a well-ventilated area.
Is this product available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product, for research and industrial applications worldwide.
How can I request a sample or a quote?
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You can request a sample or a quote by contacting our sales team directly through our website or by calling us. Please provide the product name and CAS number for prompt service.
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