1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea
1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea (CAS: 107819-90-9) is a specialised organic compound with a molecular weight of 290.38 g/mol. It serves as a valuable reagent primarily within chemical biology and synthesis, particularly in peptide chemistry. Its structure lends itself to applications in guanidine protection and guanidinylation processes, facilitating complex molecular constructions in research and development settings.
- IUPAC
- 1,3-Di-Boc-2-methylisothiourea,N,N′-Bis(tert-butoxycarbonyl)-S-methylisothiourea,N,N′-Di-Boc-S-methylisothiourea
- Synonyms
- 1,3-Di-Boc-2-methylisothioureaN,N′-Bis(tert-butoxycarbonyl)-S-methylisothioureaN,N′-Di-Boc-S-methylisothiourea

Peptide Synthesis
This compound acts as a protected form of thiourea, useful in peptide chemistry for introducing specific guanidine functionalities or protecting amino groups during solid-phase or solution-phase synthesis.
Guanidine Protection/Guanidinylation
It facilitates the controlled introduction or protection of guanidine groups, essential for modifying peptides and proteins or synthesising guanidine-containing small molecules.
Chemical Synthesis Reagent
Employed as a versatile building block in organic synthesis, enabling the construction of complex heterocyclic compounds and other nitrogen-containing molecules.
Chemical Biology Research
Its specific reactivity profile makes it a useful tool for researchers investigating biological pathways or developing novel biologically active compounds.
| Molecular weight | 290.38 |
|---|---|
| Linear formula | (CH3)3CO2CN=C(SCH3)NHCO2C(CH3)3 |
| Assay | 98% |
| Melting point | 115-121 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea used for?
+
This compound is primarily used in chemical biology and chemical synthesis, particularly for guanidine protection/guanidinylation and in peptide chemistry.
What is the CAS number and formula for this chemical?
+
The CAS number is 107819-90-9 and its linear formula is (CH3)3CO2CN=C(SCH3)NHCO2C(CH3)3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound at a purity of 98%. It is suitable for research and technical applications. We do not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations?
+
Handle with care, using appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany.
Is this product suitable for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea.
How can I request a sample or quote?
+
Please contact our sales team via the website or direct enquiry line to request a sample or a quotation for 1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis