(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol
(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol (CAS 212378-89-7) is a chiral compound with the molecular formula C24H31NO2 and a molecular weight of 365.51 g/mol. This organocatalyst plays a crucial role in asymmetric synthesis, particularly in oxidation reactions. It is employed in vanadium-catalyzed oxidation processes, often in conjunction with hydrogen peroxide, enabling stereoselective transformations.
- IUPAC
- (1S,2R)-1-((2-Hydroxy-3,5-di-tert-butylbenzylidene)amino)indan-2-ol
- Synonyms
- 212378-89-7C24H31NO2(1S,2R)-1-((2-Hydroxy-3,5-di-tert-butylbenzylidene)amino)indan-2-ol
![(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol (C24H31NO2) — chemical structure, CAS 212378-89-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F212378-89-7.png&w=3840&q=75)
Asymmetric Oxidation Catalysis
This compound serves as a chiral ligand in vanadium-catalyzed oxidation reactions. It facilitates the stereoselective oxidation of sulfides, a key transformation in the synthesis of chiral sulfoxides.
Chiral Ligand Synthesis
As a valuable component in asymmetric synthesis, it is utilized in the preparation of complex chiral molecules. Its structure is well-suited for directing stereochemical outcomes in catalytic processes.
Chemical Synthesis Reagent
It is employed as a reagent in various organic synthesis pathways where precise control over stereochemistry is required. Its application contributes to the development of enantiomerically pure compounds.
| Molecular weight | 365.51 |
|---|---|
| Empirical formula | C24H31NO2 |
| Assay | 97% |
| Application | Used in the vanadium-catalyzed oxidation of sulfides in conjunction with hydrogen peroxide.1 |
| Melting point | 128-131 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol used for?
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(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol is used as a chiral ligand in asymmetric synthesis, particularly in vanadium-catalyzed oxidation reactions of sulfides.
What is the CAS number and formula for this compound?
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The CAS number is 212378-89-7 and the empirical formula is C24H31NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a minimum purity of 97%. It is suitable for research and chemical synthesis applications and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations when handling this chemical?
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This compound is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quote or sample of (1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol.
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