(1R,2R)-trans-2-Acetoxy-1-cyclopentanol
(1R,2R)-trans-2-Acetoxy-1-cyclopentanol (CAS: 105663-22-7) is a chiral building block with the molecular formula C7H12O3 and a molecular weight of 144.17 g/mol. This optically active alcohol is derived from (R,R)-trans-1,2-cyclopentanediol, offering high enantiomeric purity. It serves as a valuable intermediate in asymmetric synthesis and general organic chemical synthesis, facilitating the construction of complex chiral molecules.
- IUPAC
- (1R)-trans-1,2-Cyclopentanediol monoacetate
- Synonyms
- C7H12O3(1R)-trans-1,2-Cyclopentanediol monoacetate

Chiral Synthesis Intermediate
This compound is utilized as a key intermediate in the synthesis of enantiomerically pure target molecules. Its defined stereochemistry makes it suitable for applications requiring precise molecular architecture.
Asymmetric Synthesis
As a chiral building block, (1R,2R)-trans-2-Acetoxy-1-cyclopentanol is employed in asymmetric synthesis strategies to introduce or maintain chirality in organic molecules. This is crucial for the development of pharmaceuticals and fine chemicals.
Organic Building Block
This molecule functions as a versatile organic building block, enabling chemists to construct more complex structures with controlled stereochemistry. It is useful in diverse synthetic pathways within academic and industrial research.
| Molecular weight | 144.17 |
|---|---|
| Empirical formula | C7H12O3 |
| Assay | ≥99.0% (sum of enantiomers, GC) |
| Density | 1.102 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.455 |
| Optical activity | [α]20/D +31±2°, c = 1% in chloroform |
| Optical purity | enantiomeric ratio: ≥98:2 (GC) |
| Application | Chiral alcohol derived from (R,R)-trans-1,2-cyclopentanediol |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Safety statements (S) | 23-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-trans-2-Acetoxy-1-cyclopentanol used for?
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(1R,2R)-trans-2-Acetoxy-1-cyclopentanol is used as a chiral building block and intermediate in asymmetric synthesis and general organic chemical synthesis.
What is the CAS number and formula for (1R,2R)-trans-2-Acetoxy-1-cyclopentanol?
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The CAS number is 105663-22-7, and the empirical formula is C7H12O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2R)-trans-2-Acetoxy-1-cyclopentanol with an assay of ≥99.0% (sum of enantiomers, GC) and an enantiomeric ratio of ≥98:2 (GC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling recommendations for this chemical?
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For safe handling, it is recommended to wear Eyeshields and Gloves. The safety statements suggest avoiding breathing vapours and contact with skin and eyes (S23-24/25). This substance has a WGK Germany rating of 3, indicating it is hazardous to water.
How is this chemical packed and shipped?
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Tech Serve Solutions securely packs and ships chemicals globally, adhering to all relevant transport regulations for hazardous materials. Please contact us for specific export and shipping details.
How can I request a sample or a quote?
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To request a sample or a quote for (1R,2R)-trans-2-Acetoxy-1-cyclopentanol, please use the contact form on our website or reach out to our sales department directly.
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