(1R,2R)-trans-2-(1-Piperidinyl)cyclohexylamine
(1R,2R)-trans-2-(1-Piperidinyl)cyclohexylamine (CAS 885677-91-8) is a chiral amine with the molecular formula C11H22N2 and a molecular weight of 182.31. This heterocyclic compound serves as a valuable building block in organic synthesis. Its stereochemistry makes it particularly useful in asymmetric synthesis for the creation of complex chiral molecules, offering precise control in stereoselective reactions.
- Synonyms
- C11H22N2

Chiral Building Block
Utilised in asymmetric synthesis to construct complex chiral molecules with specific stereochemistry. Its defined chirality is crucial for stereoselective transformations in pharmaceutical and fine chemical research.
Organic Synthesis Intermediate
Serves as a key intermediate in multi-step organic synthesis pathways. The presence of both a piperidine and a cyclohexylamine moiety allows for diverse chemical modifications.
Catalyst Ligand Development
Can be employed in the development of chiral ligands for transition metal catalysis. Its structure may lend itself to creating catalysts that promote enantioselective reactions.
| Molecular weight | 182.31 |
|---|---|
| Empirical formula | C11H22N2 |
| Assay | ≥97.0% (GC) |
| Optical activity | [α]/D -53.0±1.5°, c = 1 in chloroform |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-trans-2-(1-Piperidinyl)cyclohexylamine used for?
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(1R,2R)-trans-2-(1-Piperidinyl)cyclohexylamine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in general chemical synthesis.
What is the CAS number and molecular formula for this compound?
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The CAS number is 885677-91-8, and the molecular formula is C11H22N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97.0% (GC). This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should (1R,2R)-trans-2-(1-Piperidinyl)cyclohexylamine be handled?
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This compound causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing, in a well-ventilated area. In case of contact, rinse immediately with plenty of water and seek medical advice.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange international shipment for (1R,2R)-trans-2-(1-Piperidinyl)cyclohexylamine.
How can I request a quote or sample?
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To request a quote or sample, please visit our website or contact our sales team directly with your requirements.
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