(1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride
(1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride (CAS: 1030390-38-5) is a chiral diamine with a molecular weight of 173.08 g/mol. Supplied as a dihydrochloride salt, this compound serves as a valuable building block in asymmetric synthesis and organic chemistry. Its specific stereochemistry makes it useful for creating enantiomerically pure target molecules, particularly in pharmaceutical research and development and advanced chemical manufacturing processes.
- Synonyms
- 1030390-38-5C5H12N2 · 2HCl

Chiral Ligand Synthesis
This diamine is a key precursor for developing chiral ligands used in asymmetric catalysis. These ligands are crucial for controlling stereoselectivity in various organic transformations.
Asymmetric Synthesis
Serves as a chiral auxiliary or building block in the synthesis of enantiomerically pure compounds. Its defined stereocenters are transferred to target molecules, enabling stereoselective synthesis pathways.
Pharmaceutical Intermediates
Used in the multi-step synthesis of active pharmaceutical ingredients (APIs) where specific stereoisomers are required for therapeutic efficacy and safety.
Research and Development
A fundamental reagent for academic and industrial research laboratories exploring new synthetic methodologies and developing novel chiral molecules.
| Molecular weight | 173.08 |
|---|---|
| Empirical formula | C5H12N2 · 2HCl |
| Assay | 98.5-101.5% (AT) |
| Optical activity | [α]/D -22.5±1°, c = 2 in 1 M HCl |
| Storage temperature | 2-8°C |
| Impurities tested | ≤3.0% water |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride used for?
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(1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride is primarily used as a chiral building block in asymmetric synthesis and for the development of chiral ligands for asymmetric catalysis, particularly in pharmaceutical research and development.
What is the CAS number and formula for (1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride?
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The CAS number is 1030390-38-5, and its empirical formula as the dihydrochloride salt is C5H12N2 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride with an assay of 98.5-101.5%. This product is not specified as USP, BP, EP, or other pharmacopoeia grade and should be considered for technical or research purposes.
How should (1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride be handled?
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Handle with appropriate personal protective equipment, including a dust mask (N95 type recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound may cause skin, eye, and respiratory irritation (H315, H319, H335).
Is (1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride a controlled substance?
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Based on the provided data, there is no indication that (1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride is a controlled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details will be provided upon inquiry, adhering to all relevant international regulations.
How can I request a quote or sample?
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To request a quote or sample of (1R,2R)-trans-1,2-Cyclopentanediamine dihydrochloride, please contact our sales department through the website or direct inquiry channels.
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