(1R,2R)-trans-1,2-Cyclohexanediol
(1R,2R)-trans-1,2-Cyclohexanediol (CAS 1072-86-2) is a chiral diol with the molecular formula C6H12O2 and a molecular weight of 116.16 g/mol. This optically active compound, typically supplied at 99% purity, serves as a valuable chiral building block in organic synthesis. Its defined stereochemistry makes it particularly useful in asymmetric synthesis for creating complex molecules with specific spatial arrangements, finding applications in pharmaceuticals and fine chemicals.
- IUPAC
- (1R)-trans-1,2-Cyclohexanediol
- Synonyms
- 1072-86-2, C6H10(OH)2, (1R)-trans-1,2-Cyclohexanediol
Chiral Auxiliary in Asymmetric Synthesis
The defined stereochemistry of (1R,2R)-trans-1,2-cyclohexanediol allows it to be used as a chiral auxiliary, directing the stereochemical outcome of reactions to produce enantiomerically enriched products.
Precursor for Chiral Ligands
It serves as a key precursor in the synthesis of chiral ligands, which are essential for asymmetric catalysis in the pharmaceutical and fine chemical industries.
Building Block for Complex Molecules
As an organic building block, it is incorporated into the synthesis of more complex chiral molecules, including natural products and drug candidates.
| Molecular weight | 116.16 |
|---|---|
| Linear formula | C6H10(OH)2 |
| Assay | 99% |
| Optical activity | [α]20/D −39°, c = 1.6 in H2O |
| Optical purity | ee: 99% (HPLC) |
| Melting point | 107-109 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 134 °C / 273.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-trans-1,2-cyclohexanediol used for?
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(1R,2R)-trans-1,2-cyclohexanediol is primarily used as a chiral building block in asymmetric synthesis and as a precursor for chiral ligands.
What is the CAS number and chemical formula for (1R,2R)-trans-1,2-cyclohexanediol?
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The CAS number is 1072-86-2, and its linear formula is C6H10(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2R)-trans-1,2-cyclohexanediol at an assay of 99% with high optical purity (ee: 99%). This is suitable for research and chemical synthesis purposes; it is not represented as USP, BP, or EP grade.
How should (1R,2R)-trans-1,2-cyclohexanediol be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The compound has a flash point of 134 °C.
Is (1R,2R)-trans-1,2-cyclohexanediol a controlled substance?
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Based on the provided data, (1R,2R)-trans-1,2-cyclohexanediol is not indicated as a controlled substance.
How is this chemical packed and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, ensuring secure and compliant packaging for international shipment.
How can I request a sample or quote for (1R,2R)-trans-1,2-cyclohexanediol?
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Please contact our sales team via the website to request a sample or a quotation for (1R,2R)-trans-1,2-cyclohexanediol.
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