(1R)-(−)-10-Camphorsulfonyl chloride
(1R)-(−)-10-Camphorsulfonyl chloride (CAS: 39262-22-1, C10H15ClO3S) is a chiral sulfonyl chloride derived from camphor. With a molecular weight of 250.74 g/mol, this compound is primarily utilised in asymmetric synthesis. It serves as a valuable chiral building block and resolving agent for the synthesis of enantiomerically pure compounds. Its applications are significant in organic synthesis and the development of chiral pharmaceuticals.
- IUPAC
- (−)-Camphor-10-sulfonyl chloride,(1R)-Camphor-10-sulfonic acid chloride
- Synonyms
- (−)-Camphor-10-sulfonyl chloride,(1R)-Camphor-10-sulfonic acid chloride
Chiral Resolving Agent
(1R)-(−)-10-Camphorsulfonyl chloride is extensively employed as a chiral resolving agent. It reacts with racemic mixtures of amines and alcohols to form diastereomeric salts or esters, which can then be separated by physical methods such as crystallisation.
Asymmetric Synthesis
This compound functions as a chiral auxiliary and building block in asymmetric synthesis. Its inherent chirality allows for the stereoselective introduction of functional groups, leading to the formation of enantiomerically enriched products.
Intermediate in Organic Synthesis
As a reactive sulfonyl chloride, it is a versatile intermediate for synthesising various organic compounds. It readily undergoes reactions with nucleophiles, enabling the construction of complex molecules, including pharmaceutical intermediates.
| Molecular weight | 250.74 |
|---|---|
| Empirical formula | C10H15ClO3S |
| Assay | 97% |
| Optical activity | [α]18/D −33°, c = 3 in chloroform |
| Melting point | 66-68 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R)-(−)-10-Camphorsulfonyl chloride used for?
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(1R)-(−)-10-Camphorsulfonyl chloride is primarily used as a chiral resolving agent and in asymmetric synthesis. It serves as a valuable building block for creating enantiomerically pure compounds, particularly in the pharmaceutical and fine chemical industries.
What is the CAS number and formula for (1R)-(−)-10-Camphorsulfonyl chloride?
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The CAS number is 39262-22-1 and the empirical formula is C10H15ClO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R)-(−)-10-Camphorsulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should (1R)-(−)-10-Camphorsulfonyl chloride be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment, including eyeshields, face shields, gloves, and a suitable respirator. Always consult the Safety Data Sheet (SDS) before use.
Is (1R)-(−)-10-Camphorsulfonyl chloride suitable for export?
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Yes, Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, including (1R)-(−)-10-Camphorsulfonyl chloride, adhering to all necessary regulations for international shipment.
How can I request a sample or quote for (1R)-(−)-10-Camphorsulfonyl chloride?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (39262-22-1).
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