(1R)-(+)-(1-Amino-2-methylpropyl)phosphonic acid
(1R)-(+)-(1-Amino-2-methylpropyl)phosphonic acid (CAS 66254-56-6) is a chiral phosphonic acid derivative with the linear formula (CH3)2CHCH(NH2)P(O)(OH)2 and a molecular weight of 153.12 g/mol. It functions as a valuable building block in organic synthesis, particularly in asymmetric synthesis. Its structural similarity to amino carboxylic acids allows for its use in creating peptide analogs and as a precursor for various biologically active compounds.
Peptide Analogues
This phosphonic acid can serve as a substitute for amino carboxylic acids in biological systems, enabling the synthesis of novel peptide analogues with potentially modified properties and stability.
Antiviral Agents
The compound has been explored for its potential as an antiviral agent, contributing to the development of new therapeutic strategies against viral infections.
Catalytic Antibodies
It acts as a hapten for the generation of catalytic antibodies, facilitating research in antibody-based catalysis and immunotherapy.
Enzyme Inhibitors
With its phosphonic acid moiety, it can function as a potent enzyme inhibitor, finding applications in medicinal chemistry and biochemical research.
Agrochemicals
Its structure suggests utility in the development of herbicides and pesticides, contributing to the agrochemical industry.
| Molecular weight | 153.12 |
|---|---|
| Linear formula | (CH3)2CHCH(NH2)P(O)(OH)2 |
| Assay | 98% |
| Optical activity | [α]20/D +1.0°, c = 1 in 1 M NaOH |
| Application | Serves as an attractive substitute for amino carboxylic acids in biological systems. Exhibits interesting and useful properties as peptide analog,1 antiviral agent,2 hapten for the generation of catalytic antibodies,3 enzyme inhibitors,4,5 potent antibiotics,6 herbicides, and pesticides. |
| Melting point | 272-277 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R)-(+)-(1-Amino-2-methylpropyl)phosphonic acid used for?
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This compound is used as a chiral building block in asymmetric synthesis, for creating peptide analogues, as a potential antiviral agent, a hapten for catalytic antibodies, an enzyme inhibitor, and in the development of herbicides and pesticides.
What is the CAS number and formula for this product?
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The CAS number is 66254-56-6 and the linear formula is (CH3)2CHCH(NH2)P(O)(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a purity of 98%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations for handling this chemical?
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This product is a Warning material with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
Is this product available for export globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product is available for international export.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact our sales team through the website or by calling us directly. Please reference the product name and CAS number.
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