12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid

CAS 54397-83-010EBiochemicals & Reagents

12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid (CAS 54397-83-0) is a C20H32O3 fatty acid with a molecular weight of 320.47. This hydroxy fatty acid is a key component within the arachidonic acid cascade, playing roles in cellular signalling. It is supplied by Tech Serve Solutions as a research-grade chemical, typically shipped under dry ice conditions to maintain its integrity for laboratory applications.

IUPAC: (S)-12-HETE
Synonyms: 12(S)-HETE(5Z,8Z,10E,14Z)-12-Hydroxy-eicosatetraenoic acid54397-83-0C20H32O3

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12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid (10E) — chemical structure, CAS 54397-83-0; Life Science, fine chemical supplied by Tech Serve Solutions

Arachidonic Acid CascadeBioactive Small MoleculesBiochemicals and ReagentsCell BiologyFatty Acids and conjugatesFatty AcylsHydroxy fatty acidsLipidsLipids in Cell SignalingOxylipins

01 /Applications

Research and Development

Used as a biochemical reagent in research laboratories investigating lipid metabolism and cell signalling pathways. Its role in the arachidonic acid cascade makes it valuable for studying inflammatory responses and related biological processes.

Biochemical Analysis

Serves as an analytical standard or reference compound in mass spectrometry and chromatography for the identification and quantification of oxylipins and related eicosanoids. Essential for accurate research in biochemistry and molecular biology.

Cell Biology Studies

Employed in studies focusing on cellular functions, particularly those involving membrane dynamics and signal transduction. Its involvement in lipid signaling pathways aids in understanding complex cellular mechanisms.

02 /Properties

Molecular weight	320.47
Empirical formula	C20H32O3
Assay	≥95% (HPLC)
Concentration	~100 μg/mL in ethanol
Storage temperature	−20°C

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

Danger

Hazard statements

H225Highly flammable liquid and vapour

Precautionary statements

P210Keep away from heat, sparks and open flames. No smoking

Flash point	14 °C / 57.2 °F
Transport (UN / ADR)	UN 1170C 3 / PGII
Water hazard class (WGK, DE)	1
Hazard codes (EU)	F
Risk statements (R)	11
Safety statements (S)	7-16

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

54397-83-0

MDL number

MFCD00036916

PubChem substance

24895806

Beilstein registry

2656104

05 /Additional specifications

Shipped In	dry ice

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid used for?

This compound is primarily used in biochemical research, particularly for studying the arachidonic acid cascade, lipid metabolism, and cell signalling pathways. It also serves as an analytical standard in biochemical analysis.

What is the CAS number and chemical formula for 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid?

The CAS number is 54397-83-0, and the empirical formula is C20H32O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of ≥95% (HPLC). It is considered a research-grade chemical and is not supplied as USP, BP, or EP grade.

What are the primary safety concerns when handling this chemical?

This compound is highly flammable (H225) and requires handling with care. It has a low flash point of 14°C (57.2°F). Ensure adequate ventilation, avoid ignition sources, and use appropriate personal protective equipment.