1-Phenylvinylzinc bromide solution
1-Phenylvinylzinc bromide solution (CAS: 151073-86-8) is an organozinc halide supplied by Tech Serve Solutions. With the linear formula H₂C=C(C₆H₅)ZnBr and a molecular weight of 248.44 g/mol, this reagent is typically offered as a 0.5 M solution in THF. It is a valuable intermediate in organic synthesis, particularly for carbon-carbon bond formation through cross-coupling reactions, and is favoured for its controlled reactivity and versatility in constructing complex molecular architectures.
Organozinc Reagent in Cross-Coupling Reactions
1-Phenylvinylzinc bromide solution serves as a key organometallic reagent in various palladium- or nickel-catalysed cross-coupling reactions, such as Negishi couplings. It enables the introduction of a styryl group onto diverse organic substrates, facilitating the synthesis of complex molecules.
Synthesis of Complex Organic Molecules
This organozinc halide is instrumental in the multi-step synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its application allows for precise control over stereochemistry and regiochemistry in the formation of new carbon-carbon bonds.
Preparation of Alkenyl Compounds
The reagent is utilized for the efficient synthesis of functionalised alkenes and styrenyl derivatives. Its reactive nature, coupled with the stability of organozinc compounds, makes it a preferred choice for chemists seeking reliable methods for vinyl group introduction.
| Molecular weight | 248.44 |
|---|---|
| Linear formula | H2C=C(C6H5)ZnBr |
| Boiling point | 65 °C |
| Density | 0.974 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-14-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Phenylvinylzinc bromide solution used for?
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1-Phenylvinylzinc bromide solution is primarily used as an organometallic reagent in organic synthesis, particularly for carbon-carbon bond formation in cross-coupling reactions like the Negishi coupling, and for the synthesis of complex organic molecules.
What is the CAS number and formula for 1-Phenylvinylzinc bromide solution?
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The CAS number for 1-Phenylvinylzinc bromide solution is 151073-86-8, and its linear formula is H₂C=C(C₆H₅)ZnBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Phenylvinylzinc bromide solution as a 0.5 M concentration in THF. For specific assay details or lot-specific information, please contact our sales team. TSS does not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 1-Phenylvinylzinc bromide solution be handled?
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1-Phenylvinylzinc bromide solution is a flammable liquid and vapour (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). Handle in a well-ventilated area, away from ignition sources, and wear appropriate personal protective equipment. It may form explosive peroxides and should be stored under inert gas.
Is 1-Phenylvinylzinc bromide solution a controlled substance?
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Based on the provided data, there is no indication that 1-Phenylvinylzinc bromide solution is a controlled substance.
How is 1-Phenylvinylzinc bromide solution shipped?
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As a hazardous material (UN 2924, 8(3) / PGII), 1-Phenylvinylzinc bromide solution is packaged and shipped according to strict international regulations for flammable and corrosive substances.
How can I request a quote or sample?
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To request a quote or a sample of 1-Phenylvinylzinc bromide solution, please contact the Tech Serve Solutions sales department via our website or by phone.
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