1-Nitropyrene
1-Nitropyrene (CAS 5522-43-0, C16H9NO2) is a polycyclic aromatic hydrocarbon (PAH) derivative with a molecular weight of 247.25 g/mol. This compound is primarily recognised for its utility in cancer research and as a reference standard in studies of environmental carcinogens. Its specific chemical properties make it a valuable tool for investigating mutagenic pathways and genotoxicity.

Carcinogenesis Research
Used as a model compound to study the mechanisms of DNA damage and mutation induced by polycyclic aromatic hydrocarbons. It aids in understanding the metabolic activation pathways leading to genotoxicity.
Environmental Monitoring
Serves as an analytical standard for the detection and quantification of nitro-PAHs in environmental samples, such as air particulate matter and combustion products.
Cell Biology Studies
Investigates cellular responses to genotoxic agents, including cell cycle arrest, apoptosis, and DNA repair mechanisms. Useful for evaluating the efficacy of protective agents against PAH-induced damage.
| Molecular weight | 247.25 |
|---|---|
| Empirical formula | C16H9NO2 |
| Assay | 99% |
| Melting point | 153-155 °C(lit.) |

Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Nitropyrene used for?
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1-Nitropyrene is primarily used in cancer research, as a reference standard for carcinogens, and in cell biology studies investigating genotoxicity and mutagenic pathways.
What is the CAS number and formula for 1-Nitropyrene?
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The CAS number for 1-Nitropyrene is 5522-43-0, and its molecular formula is C16H9NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Nitropyrene with an assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is suitable for research and laboratory use.
How should 1-Nitropyrene be handled safely?
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1-Nitropyrene is classified as a suspected carcinogen (H351). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (e.g., N100 US, P3 EN143). Ensure adequate ventilation and avoid dust formation (P281).
Is 1-Nitropyrene shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Nitropyrene, adhering to all relevant international shipping regulations.
How can I request a quote or sample of 1-Nitropyrene?
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To request a quote or sample of 1-Nitropyrene, please contact our sales team through the website or by calling us directly. Specify the quantity required for accurate pricing and availability.
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