1-Methylhistamine dihydrochloride
1-Methylhistamine dihydrochloride (CAS: 6481-48-7; Formula: C6H11N3 · 2HCl) is a bioactive small molecule and a neurotransmitter research chemical. This compound, with a molecular weight of 198.09 g/mol, functions as an agonist in biological research. It is primarily utilised in cell biology and neuroscience studies, specifically in investigations of cell signaling and neurotransmission pathways. It is supplied as a powder for laboratory use.
- IUPAC
- 1-Methyl-4-(β-aminoethyl)imidazole dihydrochloride

Neuroscience Research
1-Methylhistamine dihydrochloride serves as a tool in neuroscience to investigate histamine receptor signaling. It aids in understanding neurotransmission mechanisms and the role of histamine in the central nervous system.
Cell Signaling Studies
This compound is employed in cell biology to explore cellular responses mediated by histamine receptors. Researchers use it to probe pathways involved in cell communication and physiological regulation.
Agonist Research
As a histamine receptor agonist, 1-Methylhistamine dihydrochloride is valuable for in vitro studies examining receptor activation and downstream effects. It helps in characterising the functional consequences of receptor stimulation.
| Molecular weight | 198.09 |
|---|---|
| Empirical formula | C6H11N3 · 2HCl |
| Assay | ≥98% (TLC) |
| Form | powder |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methylhistamine dihydrochloride used for?
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1-Methylhistamine dihydrochloride is used in scientific research, particularly in neuroscience and cell biology, to study histamine receptor function, cell signaling, and neurotransmission as an agonist.
What are the CAS number and formula for 1-Methylhistamine dihydrochloride?
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The CAS number is 6481-48-7 and the empirical formula is C6H11N3 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Methylhistamine dihydrochloride with a purity of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.
How should 1-Methylhistamine dihydrochloride be handled and stored?
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Handle 1-Methylhistamine dihydrochloride with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Store at 2-8°C. Avoid breathing dust, ensure adequate ventilation, and avoid contact with eyes, skin, and clothing.
Is 1-Methylhistamine dihydrochloride a controlled substance?
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The provided data does not indicate that 1-Methylhistamine dihydrochloride is a controlled substance.
How is 1-Methylhistamine dihydrochloride packed and exported?
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1-Methylhistamine dihydrochloride is supplied as a powder. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a quote or sample?
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To request a quote or sample of 1-Methylhistamine dihydrochloride, please contact our sales team via the website or listed contact details.
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