1-Methyl-1-phenylhydrazine
1-Methyl-1-phenylhydrazine (CAS 618-40-6), with the molecular formula C6H5N(CH3)NH2 and a molecular weight of 122.17 g/mol, is an organic compound classified as a hydrazine derivative. It serves as a valuable building block in organic synthesis, particularly in the development of novel chemical entities and pharmaceutical intermediates. Its characteristic structure facilitates various chemical transformations for research and development purposes.
- IUPAC
- α-Methylphenylhydrazine,N-Methyl-N-phenylhydrazine
- Synonyms
- α-MethylphenylhydrazineN-Methyl-N-phenylhydrazine

Organic Synthesis Intermediate
1-Methyl-1-phenylhydrazine is employed as a key intermediate in complex organic syntheses. It is utilised in the construction of heterocyclic compounds and other functionalised molecules essential for drug discovery and materials science research.
Pharmaceutical Research
This compound finds application in the synthesis of potential drug candidates and pharmaceutical intermediates. Its reactive nature allows for its incorporation into diverse molecular scaffolds during medicinal chemistry research.
Chemical Reagent
As a substituted hydrazine, it can act as a versatile reagent in various chemical transformations, contributing to the development of new synthetic methodologies and reaction pathways in academic and industrial laboratories.
| Molecular weight | 122.17 |
|---|---|
| Linear formula | C6H5N(CH3)NH2 |
| Assay | 97% |
| Boiling point | 54-55 °C/0.3 mmHg(lit.) |
| Density | 1.038 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.583(lit.) |
| Storage temperature | 2-8°C |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 92 °C / 197.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methyl-1-phenylhydrazine used for?
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1-Methyl-1-phenylhydrazine is primarily used as an intermediate in organic synthesis, particularly for building blocks in chemical synthesis, and in pharmaceutical research.
What are the CAS number and formula for 1-Methyl-1-phenylhydrazine?
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The CAS number for 1-Methyl-1-phenylhydrazine is 618-40-6, and its molecular formula is C6H5N(CH3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Methyl-1-phenylhydrazine with an assay of 97%. This is a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 1-Methyl-1-phenylhydrazine be handled safely?
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Handling requires appropriate personal protective equipment including eyeshields, face shields, and gloves. Use in a well-ventilated area or with a suitable respirator. Refer to the Safety Data Sheet for comprehensive handling procedures, as it is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation.
How is 1-Methyl-1-phenylhydrazine packed and shipped?
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1-Methyl-1-phenylhydrazine is packed and shipped according to relevant regulations for hazardous materials, adhering to safety standards for transportation.
How can I request a sample or quote for 1-Methyl-1-phenylhydrazine?
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To request a sample or obtain a quotation, please contact the Tech Serve Solutions sales team through our website or by phone, referencing the product name and CAS number.
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