1-Hydroxybenzotriazole hydrate
1-Hydroxybenzotriazole hydrate (CAS 123333-53-9), molecular formula C6H5N3O · xH2O, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- HOBt Hydrate

| Molecular weight | 135.12 (anhydrous basis) |
|---|---|
| Empirical formula | C6H5N3O · xH2O |
| Assay | 97% |
| Application | Additive used in oligonucleotide couplings1,2 and in racemization-free peptide couplings.3,4 |
| Melting point | 155-158 °C(lit.) |

Hazard statements
- H228Flammable solid
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Transport (UN / ADR) | UN 3380 4.1/PG 1 |
|---|---|
| Water hazard class (WGK, DE) | nwg |
| Hazard codes (EU) | F |
| Risk statements (R) | 1-11-44 |
| Safety statements (S) | 26-37-60 |
| Supplemental hazards | Explosive when dry., Risk of explosion if heated under confinement. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Quality | synthesis grade |
|---|---|
| Description | White to Off White Powder |
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Hydroxybenzotriazole hydrate?
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1-Hydroxybenzotriazole hydrate (CAS 123333-53-9), molecular formula C6H5N3O · xH2O, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of 1-Hydroxybenzotriazole hydrate does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Hydroxybenzotriazole hydrate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of 1-Hydroxybenzotriazole hydrate?
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1-Hydroxybenzotriazole hydrate has CAS number 123333-53-9 and molecular formula C6H5N3O · xH2O. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for 1-Hydroxybenzotriazole hydrate?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of 1-Hydroxybenzotriazole hydrate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should 1-Hydroxybenzotriazole hydrate be stored?
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Store 1-Hydroxybenzotriazole hydrate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is 1-Hydroxybenzotriazole hydrate used for?
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1-Hydroxybenzotriazole hydrate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for 1-Hydroxybenzotriazole hydrate?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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