N,N,2,4,6-Pentamethylaniline
N,N,2,4,6-Pentamethylaniline (CAS 13021-15-3), with the linear formula (CH₃)₃C₆H₂N(CH₃)₂, is a valuable organic building block. This amine derivative has a molecular weight of 163.26 g/mol and a purity of 98%. It is utilised in chemical synthesis, particularly in the creation of complex organic molecules. Its properties make it a useful intermediate for researchers and industrial chemists.
- IUPAC
- N,N-Dimethylmesidine
- Synonyms
- 4,6-PentamethylanilineN,N-Dimethylmesidine

Organic Synthesis Intermediate
N,N,2,4,6-Pentamethylaniline serves as a key intermediate in various organic synthesis pathways. Its structure allows for specific chemical transformations, contributing to the development of novel compounds.
Research and Development
This compound is employed in research laboratories for the synthesis of specialised chemicals and as a building block for more complex molecular structures. Its availability supports advancements in chemical research.
Synthesis of Amino Glycosides
Historically, N,N,2,4,6-Pentamethylaniline has been utilised in the synthesis of oximino glycosides, which are subsequently reduced. This demonstrates its utility in carbohydrate chemistry and related fields.
| Molecular weight | 163.26 |
|---|---|
| Linear formula | (CH3)3C6H2N(CH3)2 |
| Assay | 98% |
| Boiling point | 213-215 °C(lit.) |
| Density | 0.907 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.512(lit.) |
| Application | N,N,2,4,6-Pentamethylaniline was used in the synthesis of an oximino glycoside that was reduced with lithium aluminum hydride to benzyl 2-amino-2-deoxy-α-D-gluco- and -mannopyranoside hydrochloride. |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N,2,4,6-Pentamethylaniline used for?
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N,N,2,4,6-Pentamethylaniline is used as an intermediate in organic synthesis, for example, in the preparation of amino glycosides, and in research and development for creating complex molecules.
What is the CAS number and chemical formula for N,N,2,4,6-Pentamethylaniline?
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The CAS number is 13021-15-3 and the linear formula is (CH₃)₃C₆H₂N(CH₃)₂.
What grade and purity does Tech Serve Solutions supply for N,N,2,4,6-Pentamethylaniline?
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Tech Serve Solutions supplies N,N,2,4,6-Pentamethylaniline with an assay of 98%. This is a technical/research grade and TSS does not represent it as USP, BP, or EP.
How should N,N,2,4,6-Pentamethylaniline be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection. It is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and respiratory irritation.
Is N,N,2,4,6-Pentamethylaniline packed, shipped, or exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including N,N,2,4,6-Pentamethylaniline.
How can I request a sample or quote for N,N,2,4,6-Pentamethylaniline?
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Please contact our sales team directly to inquire about samples or to obtain a quotation for N,N,2,4,6-Pentamethylaniline.
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