Myristoyl chloride
Myristoyl chloride (CAS: 112-64-1) is an acyl halide with the linear formula CH₃(CH₂)₁₂COCl and a molecular weight of 246.82 g/mol. This reactive compound serves as a versatile building block in organic synthesis. It is frequently employed in acylation reactions, particularly for introducing the myristoyl moiety, a saturated fatty acid derivative, into various molecular structures for applications in material science and biochemical research.
- IUPAC
- Tetradecanoyl chloride
- Synonyms
- Tetradecanoyl chloride
Synthesis of Modified Cellulose
Myristoyl chloride has been utilised in the synthesis of novel cellulose derivatives, such as 6-azafulleroid-6-deoxy-2,3-di-O-myristoylcellulose, contributing to the development of advanced materials with tailored properties.
Chitosan Hydrophobisation for Drug Delivery
The compound facilitates the N-acylation of chitosan, a biopolymer. This process introduces hydrophobicity, making chitosan suitable for use as a matrix in controlled drug delivery systems.
Dendritic Polymer Synthesis
Myristoyl chloride is a key reagent in the synthesis of semi-crystalline dendritic poly(ether-amide) derivatives, contributing to the creation of complex macromolecular architectures.
| Molecular weight | 246.82 |
|---|---|
| Linear formula | CH3(CH2)12COCl |
| Assay | ≥99% |
| Boiling point | 250 °C/100 mmHg(lit.) |
| Density | 0.908 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.449(lit.) |
| Storage temperature | −20°C |
| Melting point | −1 °C(lit.) |
| Application | Myristoyl chloride was used in the synthesis of 6-azafulleroid-6-deoxy-2,3-di-O-myristoylcellulose1. It was used in N-acylation of chitosan to introduce hydrophobicity for use as matrix for drug delivery2. It was used in the synthesis of semi-crystalline dendritic poly(ether-amide) derivatives3. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Myristoyl chloride used for?
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Myristoyl chloride is primarily used as a reagent in organic synthesis, including the preparation of modified polymers, acylation of amines, and synthesis of various organic compounds.
What are the CAS number and formula for Myristoyl chloride?
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The CAS number is 112-64-1 and the linear formula is CH₃(CH₂)₁₂COCl.
What grade and purity does Tech Serve Solutions supply for Myristoyl chloride?
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Tech Serve Solutions supplies Myristoyl chloride with an assay of ≥99%. We do not represent this product as USP, BP, or EP grade.
How should Myristoyl chloride be handled safely?
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Myristoyl chloride is a corrosive substance (H314) causing severe skin burns and eye damage. Handle with extreme caution, using full protective equipment including gloves, goggles, face shield, and appropriate respiratory protection. Ensure good ventilation and work in a fume hood.
Is Myristoyl chloride a controlled substance?
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Based on the provided data, Myristoyl chloride is not listed as a controlled substance. However, regulations can vary by jurisdiction.
How is Myristoyl chloride packed and shipped?
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Myristoyl chloride is shipped as a hazardous material, UN 3265, Class 8, Packing Group II. Specific packaging details adhere to international transport regulations.
How can I request a quote or sample of Myristoyl chloride?
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To request a quote or sample, please contact the Tech Serve Solutions sales team through our official website or contact details provided.
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