1-Fluoro-2-nitrobenzene
1-Fluoro-2-nitrobenzene (CAS: 1493-27-2), with the molecular formula FC6H4NO2 and a molecular weight of 141.10 g/mol, is a key fluorinated organic building block. It is primarily utilised in chemical synthesis, serving as an intermediate in the production of various organic compounds. Its unique structure, featuring both a nitro group and a fluorine atom on a benzene ring, makes it valuable for introducing these functionalities into more complex molecules within research and industrial applications.

Chemical Synthesis Intermediate
This compound serves as a crucial intermediate in organic synthesis. The presence of both a fluorine atom and a nitro group allows for diverse chemical transformations, facilitating the construction of more complex organic molecules.
Pharmaceutical Research
1-Fluoro-2-nitrobenzene is employed in the synthesis of novel pharmaceutical compounds. It can be a precursor to active pharmaceutical ingredients (APIs) or key intermediates in drug discovery programs.
Agrochemical Development
The structural features of 1-Fluoro-2-nitrobenzene make it a potential building block for the development of new agrochemicals. It can be incorporated into molecules designed for crop protection or pest control.
Materials Science
As a fluorinated aromatic compound, it may find applications in the synthesis of specialized polymers or advanced materials where the unique electronic or physical properties imparted by fluorine are desired.
| Molecular weight | 141.10 |
|---|---|
| Linear formula | FC6H4NO2 |
| Assay | 99% |
| Boiling point | 116 °C/22 mmHg(lit.) |
| Density | 1.338 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.532(lit.) |
| Melting point | −9-−6 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 94 °C / 201.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Fluoro-2-nitrobenzene used for?
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1-Fluoro-2-nitrobenzene is used as a chemical synthesis intermediate, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials due to its fluorinated aromatic structure.
What is the CAS number and chemical formula for 1-Fluoro-2-nitrobenzene?
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The CAS number is 1493-27-2 and the chemical formula is FC6H4NO2.
What grade and purity does Tech Serve Solutions supply for 1-Fluoro-2-nitrobenzene?
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Tech Serve Solutions supplies 1-Fluoro-2-nitrobenzene with an assay of 99%. This product is typically for research and chemical synthesis use and is not represented as USP, BP, or EP grade.
How should 1-Fluoro-2-nitrobenzene be handled safely?
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1-Fluoro-2-nitrobenzene is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area.
How is 1-Fluoro-2-nitrobenzene packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals adhering to all relevant safety and regulatory standards for international transit.
How can I request a quote or sample for 1-Fluoro-2-nitrobenzene?
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To request a quote or sample for 1-Fluoro-2-nitrobenzene, please contact our sales department through the website or by phone.
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