1-Chloro-2-propanol
1-Chloro-2-propanol (CAS: 127-00-4) is an organic compound with a molecular weight of 94.54 g/mol. This chemical, also known as propylene chlorohydrin, is a versatile building block primarily utilised in chemical synthesis. It serves as a key intermediate in the manufacture of propylene oxide, a precursor for polyols and propylene glycol. Its properties also lend themselves to applications in biochemical research as a standard for enzymatic synthesis.
- IUPAC
- Chloropropanol,Propylene chlorohydrin
Propylene Oxide Synthesis
1-Chloro-2-propanol is a crucial intermediate in the industrial production of propylene oxide. This process is fundamental for the subsequent manufacture of polyurethane materials and propylene glycol, which have widespread applications.
Biochemical Research Standard
In enzymatic synthesis, 1-Chloro-2-propanol acts as a valuable standard for studying the formation of alpha,beta-halohydrins from gaseous alkenes. This aids in understanding and optimising biocatalytic processes.
Organic Synthesis Building Block
As an organic building block, this compound offers reactive sites for further chemical transformations. It is employed in various organic synthesis pathways where its specific structure is required.
| Molecular weight | 94.54 |
|---|---|
| Linear formula | CH3CH(OH)CH2Cl+CH3CHClCH2OH |
| Assay | 70% |
| Boiling point | 126-127 °C(lit.) |
| Density | 1.111 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.439(lit.) |
| Impurities tested | <25% 2-chloro-1-propanol |
| Application | 1-Chloro-2-propanol has been used as:• chemical intermediate for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol1• as α,β-halohydrin standard during the enzymatic synthesis of α,β-halohydrins from gaseous alkenes2 |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 52 °C / 125.6 °F |
| Transport (UN / ADR) | UN 2611 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20-36/37/38 |
| Safety statements (S) | 26-36/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Chloro-2-propanol used for?
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1-Chloro-2-propanol is used as a chemical intermediate in the manufacture of propylene oxide, and as a standard in the enzymatic synthesis of alpha,beta-halohydrins.
What is the CAS number and formula for 1-Chloro-2-propanol?
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The CAS number for 1-Chloro-2-propanol is 127-00-4. Its linear formula is CH3CH(OH)CH2Cl+CH3CHClCH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Chloro-2-propanol with an assay of 70%, containing less than 25% 2-chloro-1-propanol as an impurity. TSS does not represent this product as USP, BP, or EP grade.
How should 1-Chloro-2-propanol be handled?
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1-Chloro-2-propanol is a flammable liquid and vapour (H226), harmful if swallowed (H302), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) or be harmful if inhaled (H332). Handle with appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection.
Is 1-Chloro-2-propanol a controlled substance?
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The provided data does not indicate that 1-Chloro-2-propanol is a controlled substance.
How is 1-Chloro-2-propanol packed and shipped?
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1-Chloro-2-propanol is shipped as UN 2611, Class 6.1, Packing Group II. TSS ensures compliance with all export and shipping regulations for this chemical.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quote or a sample of 1-Chloro-2-propanol.
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