1-Chloro-2-nitrobenzene
1-Chloro-2-nitrobenzene (CAS: 88-73-3, Formula: ClC6H4NO2) is a nitro compound with a molecular weight of 157.55 g/mol. This chemical is primarily utilised as a building block in organic synthesis, particularly in the preparation of other complex molecules. Its characteristic properties make it a valuable intermediate in various chemical processes requiring specific nitro-substituted aromatic structures.

Intermediate in Organic Synthesis
1-Chloro-2-nitrobenzene serves as a crucial building block in the synthesis of various organic compounds. Its structure allows for further functionalisation, making it valuable in the development of novel molecules.
Synthesis of Specialty Chemicals
This compound is employed in the preparation of specialty chemicals, including derivatives used in research and development. Its specific reactivity profile is leveraged to create targeted molecular architectures.
Precursor for Benzotriazole Derivatives
Historically, 1-Chloro-2-nitrobenzene has been documented for its use in the synthesis of 1-hydroxybenzotriazole derivatives, highlighting its utility in specific heterocyclic chemistry pathways.
| Molecular weight | 157.55 |
|---|---|
| Linear formula | ClC6H4NO2 |
| Assay | 99% |
| Boiling point | 246 °C(lit.) |
| Density | 1.348 g/mL at 25 °C(lit.) |
| Solubility | alcohol: solublebenzene: solublediethyl ether: solublewater: insoluble |
| Vapour pressure | 0.04 mmHg (25 °C) |
| Melting point | 31-33 °C(lit.) |
| Vapour density | 5.4 (vs air) |
| Autoignition temp | 500 °F |
| Application | 1-Chloro-2-nitrobenzene was used in the synthesis of 1-hydroxybenzotriazole derivatives1. |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 126 °C / 258.8 °F |
| Transport (UN / ADR) | UN 1578 6.1 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-24-52/53 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Chloro-2-nitrobenzene used for?
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1-Chloro-2-nitrobenzene is primarily used as a building block and intermediate in organic synthesis, including the preparation of specialty chemicals and derivatives like 1-hydroxybenzotriazole.
What are the CAS number and chemical formula for 1-Chloro-2-nitrobenzene?
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The CAS number for 1-Chloro-2-nitrobenzene is 88-73-3, and its chemical formula is ClC6H4NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies 1-Chloro-2-nitrobenzene with an assay of 99%. This is generally considered a technical or research grade. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated in the product specifications.
How should 1-Chloro-2-nitrobenzene be handled safely?
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1-Chloro-2-nitrobenzene is classified with the GHS symbol GHS06 and the signal word 'Danger'. It carries hazard statements H301 + H311, indicating acute toxicity if swallowed or in contact with skin. Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, gloves, and P2 respirator cartridges, should be used. Always consult the Safety Data Sheet (SDS) before handling.
How is 1-Chloro-2-nitrobenzene packed and shipped?
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1-Chloro-2-nitrobenzene is typically packed according to UN 1578, 6.1 / PGII regulations for hazardous materials. Tech Serve Solutions ensures that all shipments comply with international export regulations for chemical products.
How can I request a quote or sample for 1-Chloro-2-nitrobenzene?
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To request a quote or a sample of 1-Chloro-2-nitrobenzene, please visit the product page on the Tech Serve Solutions website and utilise the contact form or enquiry button. Alternatively, you may contact our sales team directly.
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