Piperidine
Piperidine (CAS: 110-89-4; Formula: C5H11N; Molar Mass: 85.15 g/mol) is a colourless liquid with a strong amine odour. It is a cyclic secondary amine and a strong organic base, commonly used as a building block in organic synthesis. Piperidine and its derivatives are found in numerous pharmaceuticals and natural products. It is purified by redistillation to achieve a high assay of ≥99.5%.
- IUPAC
- Hexahydropyridine
- Synonyms
- Hexahydropyridine
Organic Synthesis Intermediate
Piperidine serves as a crucial building block in the synthesis of various organic compounds. Its nucleophilic nature makes it valuable for constructing more complex molecules, including pharmaceuticals and agrochemicals.
Pharmaceutical Synthesis
This cyclic amine is a key intermediate in the production of numerous pharmaceutical agents. Its structure is present in many pharmacologically active compounds, driving demand in drug discovery and manufacturing.
Catalysis
As a strong base, piperidine can be employed as a catalyst in certain organic reactions, facilitating transformations that require basic conditions. It is particularly useful in condensation reactions.
Solvent and Reagent
Piperidine can function as a solvent or a reagent in various chemical processes. Its ability to act as a base and a nucleophile makes it versatile in laboratory and industrial applications.
| Molecular weight | 85.15 |
|---|---|
| Empirical formula | C5H11N |
| Assay | ≥99.5% |
| Boiling point | 106 °C(lit.) |
| Density | 0.862 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.452(lit.) |
| Concentration | 20% in DMF |
| Melting point | −13 °C(lit.) |
| Vapour pressure | 23 mmHg (20 °C) |
| Vapour density | 3 (vs air) |
| Impurities tested | ≤0.1% water |
Hazard statements
- H225Highly flammable liquid and vapour
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 16 °C / 60.8 °F |
| Transport (UN / ADR) | UN 2401 3(8) / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-23/24-34 |
| Safety statements (S) | 16-26-27-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Purified By | redistillation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Piperidine used for?
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Piperidine is primarily used as a building block in organic synthesis, a key intermediate in pharmaceutical production, and can function as a catalyst or reagent in various chemical reactions.
What is the CAS number and formula for Piperidine?
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The CAS number for Piperidine is 110-89-4, and its molecular formula is C5H11N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Piperidine with an assay of ≥99.5%, purified by redistillation. We do not represent this product as USP, BP, or EP grade.
How is Piperidine handled and what are its primary hazards?
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Piperidine is a flammable liquid and vapour (H225) and is corrosive, causing severe skin burns and eye damage (H314). It is also toxic if inhaled or in contact with skin (H331, H311). Handle with appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area.
How are Piperidine products shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of chemicals, adhering to all relevant shipping and export regulations for hazardous materials like Piperidine.
How can I request a sample or a quote for Piperidine?
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Please contact our sales team via the website or directly to request a sample or obtain a quotation for Piperidine.
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